Key Echocardiographic Considerations for Tricuspid Valve Transcatheter Edge-to-Edge Repair

Chronic tricuspid regurgitation (TR) results in progressive right ventricular (RV) volume overload, followed by right-sided chamber dilatation, RV systolic dysfunction, and eventual low-output cardiac failure. Severe TR is associated with considerable morbidity and mortality, and yet until recently, patients in the late stage of their disease course had limited treatment options. Cognizant of the high mortality rates associated with surgical intervention, tricuspid valve (TV) transcatheter edge-to-edge repair (TEER) has emerged as a promising solution for patients with severe TR. As has been learned from the transcatheter mitral valve TEER experience, detailed morphological and mechanistic assessment of the TV with transthoracic and transesophageal imaging is essential to optimal patient selection and procedural success. The current review will provide a comprehensive overview of TV anatomy, the updated mechanistic classification of TR, and key echocardiographic considerations in the evaluation, management, and follow-up of patients undergoing TV TEER. •Severe TR is associated with progressive RV volume overload and RV-PA uncoupling.•TV morphological and mechanistic assessment is critical to device success.•RV size/function assessment in severe TR is complemented by 3D and STE techniques.•Postprocedural surveillance must assess durability of repair and RV/RA remodeling.