A Matrix‐Metalloproteinase‐Responsive Hydrogel System for Modulating the Immune Microenvironment in Myocardial Infarction

Injectable hydrogels carrying therapeutic factors to modulate the infarct immune microenvironment show great potential in the treatment of myocardial infarction (MI). However, conventional injectable hydrogels release therapeutic factors in an uncontrolled manner, which leads to poor treatment effic...

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Veröffentlicht in:	Advanced materials (Weinheim) 2023-03, Vol.35 (13), p.e2209041-n/a
Hauptverfasser:	Chen, Wei, Wang, Changyong, Liu, Wei, Zhao, Bicheng, Zeng, Zhicheng, Long, Fen, Wang, Chunlan, Li, Siwei, Lin, Naibo, Zhou, Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Heart attacks Hydrogels Hydrogels - pharmacology immune microenvironment Interleukins Materials science Matrix Metalloproteinases Myocardial infarction Myocardial Infarction - drug therapy Myocytes, Cardiac Photoluminescence Plasmids Polyethylene glycol Polyethylene Glycols - therapeutic use Rats responsive hydrogels Side effects
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