A systematic study of the determinants of protein abundance memory in cell lineage

Proteins are essential players of life activities. Intracellular protein levels directly affect cellular functions and cell fate. Upon cell division, the proteins in the mother cell are inherited by the daughters. However, what factors and by how much they affect this epigenetic inheritance of prote...

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Veröffentlicht in:	Science bulletin 2018-08, Vol.63 (16), p.1051-1058
Hauptverfasser:	Gao, Zongmao, Sun, Haoyuan, Qin, Shanshan, Yang, Xiaojing, Tang, Chao
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell lineage Epigenetic inheritance Extrinsic noise Intrinsic noise Protein abundance memory
Online-Zugang:	Volltext
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