Antibody-drug conjugates: in search of partners of choice

Antibody-drug conjugates (ADCs) have become a credentialled class of anticancer drugs for both solid and hematological malignancies, with regulatory approvals mainly as single agents. Despite extensive preclinical and clinical efforts to develop rational ADC-based combinations, to date only a limite...

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Veröffentlicht in:	Trends in Cancer 2023-04, Vol.9 (4), p.339-354
Hauptverfasser:	Fuentes-Antrás, Jesús, Genta, Sofia, Vijenthira, Abi, Siu, Lillian L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Humans Immunoconjugates - pharmacology Immunoconjugates - therapeutic use Neoplasms - drug therapy Tumor Microenvironment
Online-Zugang:	Volltext
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