DapNet-HLA: Adaptive dual-attention mechanism network based on deep learning to predict non-classical HLA binding sites

Human leukocyte antigen (HLA) plays a vital role in immunomodulatory function. Studies have shown that immunotherapy based on non-classical HLA has essential applications in cancer, COVID-19, and allergic diseases. However, there are few deep learning methods to predict non-classical HLA alleles. In...

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Veröffentlicht in:	Analytical biochemistry 2023-04, Vol.666, p.115075-115075, Article 115075
Hauptverfasser:	Jing, Yuanyuan, Zhang, Shengli, Wang, Houqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Bahdanau attention mechanism Binding Sites COVID-19 Deep Learning Histocompatibility Antigens Class I - metabolism HLA Antigens Humans Non-classical HLA binding sites SENet attention mechanism Word embedding
Online-Zugang:	Volltext
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