Semiautomatic macroencapsulation of large numbers of porcine hepatocytes by coextrusion with a solution of AN69 polymer

We have previously demonstrated that allogenic and xenogenic hepatocytes macroencapsulated manually in AN-69 polymer and transplanted intra-peritoneally in rats remained viable for several weeks. However, this manual technique is inadequate to encapsulate several billions of hepatocytes which would...

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Veröffentlicht in:	Biomaterials 2000-06, Vol.21 (12), p.1269-1274
Hauptverfasser:	Honiger, J., Sarkis, R., Baudrimont, M., Delelo, R., Chafai, N., Benoist, S., Sarkis, K., Balladur, P., Capeau, J., Nordlinger, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins Acrylonitrile - analogs & derivatives AN-69 polymer Animal cell culture Animals Artificial organs Automation Biological and medical sciences Capsules Cell Survival Cell Transplantation - instrumentation Cell Transplantation - methods Cells Coextrusion Dimethyl Sulfoxide Encapsulation Equipment Design Evaluation Studies as Topic Hydrogels Implantable bioartificial liver Liver - cytology Medical sciences Peritoneal Cavity Pig hepatocytes Polyacrylonitriles Prostheses and Implants Rats Rats, Inbred Lew Sodium Chloride Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Swine Technology. Biomaterials. Equipments Transplantation (surgical) Transplantation, Heterologous Transplantation, Heterotopic
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