Recurrence and risk factors in cured patients with vitiligo: A real‐life single‐center retrospective study
Background The risk of recurrence after successful repigmentation in vitiligo has attracted attention from both patients and clinicians. Objectives The recurrence rate and risk factors in cured patients with vitiligo were analyzed to improve clinical prevention and treatment. Methods Clinical record...
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| Veröffentlicht in: | Journal of cosmetic dermatology 2023-05, Vol.22 (5), p.1680-1684 |
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| creator | Xu, Wei Qiu, Zhijin Li, Chaolan Wang, Yuyi Lin, Mao Liu, Yi Wen, Yating Zheng, Wenhao |
| description | Background
The risk of recurrence after successful repigmentation in vitiligo has attracted attention from both patients and clinicians.
Objectives
The recurrence rate and risk factors in cured patients with vitiligo were analyzed to improve clinical prevention and treatment.
Methods
Clinical records of 76 patients with vitiligo who demonstrated at least 80% repigmentation were analyzed retrospectively. Single‐factor analysis of variance and binary logistic regression analysis was employed to screen the risk factors of vitiligo recurrence.
Results
Among the 76 cured patients, 26 relapsed (total recurrence rate of 34.2%). Among these, 20 relapsed within one year (recurrence rate of 26.3%). Single‐factor analysis of variance revealed significant differences (p |
| doi_str_mv | 10.1111/jocd.15637 |
| format | Article |
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The risk of recurrence after successful repigmentation in vitiligo has attracted attention from both patients and clinicians.
Objectives
The recurrence rate and risk factors in cured patients with vitiligo were analyzed to improve clinical prevention and treatment.
Methods
Clinical records of 76 patients with vitiligo who demonstrated at least 80% repigmentation were analyzed retrospectively. Single‐factor analysis of variance and binary logistic regression analysis was employed to screen the risk factors of vitiligo recurrence.
Results
Among the 76 cured patients, 26 relapsed (total recurrence rate of 34.2%). Among these, 20 relapsed within one year (recurrence rate of 26.3%). Single‐factor analysis of variance revealed significant differences (p < 0.05) with the age of onset (yr), distribution of onset, and oral traditional Chinese medicine (TCM) intake between the recurrence and nonrecurrence groups. Binary logistic regression analysis displayed that the age of onset (yr) (p = 0.015, OR = 1.051), distribution of onset (p = 0.046, OR = 0.194), and oral TCM (p = 0.018, OR = 4.360) are significant risk factors for vitiligo recurrence.
Conclusion
A total relapse rate of 34.2% was observed in cured vitiligo patients. The age of onset (yr), distribution of onset, and oral TCM are risk factors for vitiligo recurrence. The necessary interventions should be considered on these factors for reducing the recurrence rate of vitiligo.</description><identifier>ISSN: 1473-2130</identifier><identifier>EISSN: 1473-2165</identifier><identifier>DOI: 10.1111/jocd.15637</identifier><identifier>PMID: 36721299</identifier><language>eng</language><publisher>England: John Wiley & Sons, Inc</publisher><subject>Age ; Autoimmune diseases ; Chi-square test ; Chinese medicine ; Combined Modality Therapy ; Disease ; Family medical history ; Hospitals ; Humans ; Recurrence ; Regression analysis ; Retrospective Studies ; Risk factors ; Steroids ; Treatment Outcome ; Ultraviolet Therapy ; Vitiligo ; Vitiligo - epidemiology ; Vitiligo - therapy</subject><ispartof>Journal of cosmetic dermatology, 2023-05, Vol.22 (5), p.1680-1684</ispartof><rights>2023 The Authors. published by Wiley Periodicals LLC.</rights><rights>2023 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.</rights><rights>2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3527-9b09317634e64111255130864e8ab8456a94b8c62202c3bf2991485b8a31b8423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjocd.15637$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjocd.15637$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,1411,11541,27901,27902,45550,45551,46027,46451</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36721299$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xu, Wei</creatorcontrib><creatorcontrib>Qiu, Zhijin</creatorcontrib><creatorcontrib>Li, Chaolan</creatorcontrib><creatorcontrib>Wang, Yuyi</creatorcontrib><creatorcontrib>Lin, Mao</creatorcontrib><creatorcontrib>Liu, Yi</creatorcontrib><creatorcontrib>Wen, Yating</creatorcontrib><creatorcontrib>Zheng, Wenhao</creatorcontrib><title>Recurrence and risk factors in cured patients with vitiligo: A real‐life single‐center retrospective study</title><title>Journal of cosmetic dermatology</title><addtitle>J Cosmet Dermatol</addtitle><description>Background
The risk of recurrence after successful repigmentation in vitiligo has attracted attention from both patients and clinicians.
Objectives
The recurrence rate and risk factors in cured patients with vitiligo were analyzed to improve clinical prevention and treatment.
Methods
Clinical records of 76 patients with vitiligo who demonstrated at least 80% repigmentation were analyzed retrospectively. Single‐factor analysis of variance and binary logistic regression analysis was employed to screen the risk factors of vitiligo recurrence.
Results
Among the 76 cured patients, 26 relapsed (total recurrence rate of 34.2%). Among these, 20 relapsed within one year (recurrence rate of 26.3%). Single‐factor analysis of variance revealed significant differences (p < 0.05) with the age of onset (yr), distribution of onset, and oral traditional Chinese medicine (TCM) intake between the recurrence and nonrecurrence groups. Binary logistic regression analysis displayed that the age of onset (yr) (p = 0.015, OR = 1.051), distribution of onset (p = 0.046, OR = 0.194), and oral TCM (p = 0.018, OR = 4.360) are significant risk factors for vitiligo recurrence.
Conclusion
A total relapse rate of 34.2% was observed in cured vitiligo patients. The age of onset (yr), distribution of onset, and oral TCM are risk factors for vitiligo recurrence. The necessary interventions should be considered on these factors for reducing the recurrence rate of vitiligo.</description><subject>Age</subject><subject>Autoimmune diseases</subject><subject>Chi-square test</subject><subject>Chinese medicine</subject><subject>Combined Modality Therapy</subject><subject>Disease</subject><subject>Family medical history</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Recurrence</subject><subject>Regression analysis</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>Steroids</subject><subject>Treatment Outcome</subject><subject>Ultraviolet Therapy</subject><subject>Vitiligo</subject><subject>Vitiligo - epidemiology</subject><subject>Vitiligo - therapy</subject><issn>1473-2130</issn><issn>1473-2165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kU1OwzAUhC0EoqWw4QDIEhuE1OKfxEnYVeVflZAQrC3HeQGXNCm2A-qOI3AEzsJROAkuhS5Y4M2zNZ9GnjcI7VIyoOEcTRpdDGgseLKGujRKeJ9REa-v7px00JZzE0JoktF4E3W4SBhlWdZFzQ3o1lqoNWBVF9ga94hLpX1jHTY1DiIUeKa8gdo7_GL8A3423lTmvjnGw493C6r6fH2rTAnYmfq-gvDSAQaLLXjbuBlob56D6ttivo02SlU52PmZPXR3dno7uuiPr88vR8NxX_OYJf0sJxmnieARiChkZHEcYqQiglTlaRQLlUV5qgVjhGmelyELjdI4TxWnQWe8hw6WvjPbPLXgvJwap6GqVA1N6yRLEip4xhkP6P4fdNK0tg6_k5xkRFAeiQV1uKR0iOQslHJmzVTZuaRELmqQixrkdw0B3vuxbPMpFCv0d-8BoEvgxVQw_8dKXl2PTpamX40Zk_E</recordid><startdate>202305</startdate><enddate>202305</enddate><creator>Xu, Wei</creator><creator>Qiu, Zhijin</creator><creator>Li, Chaolan</creator><creator>Wang, Yuyi</creator><creator>Lin, Mao</creator><creator>Liu, Yi</creator><creator>Wen, Yating</creator><creator>Zheng, Wenhao</creator><general>John Wiley & Sons, Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>202305</creationdate><title>Recurrence and risk factors in cured patients with vitiligo: A real‐life single‐center retrospective study</title><author>Xu, Wei ; Qiu, Zhijin ; Li, Chaolan ; Wang, Yuyi ; Lin, Mao ; Liu, Yi ; Wen, Yating ; Zheng, Wenhao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3527-9b09317634e64111255130864e8ab8456a94b8c62202c3bf2991485b8a31b8423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Age</topic><topic>Autoimmune diseases</topic><topic>Chi-square test</topic><topic>Chinese medicine</topic><topic>Combined Modality Therapy</topic><topic>Disease</topic><topic>Family medical history</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Recurrence</topic><topic>Regression analysis</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>Steroids</topic><topic>Treatment Outcome</topic><topic>Ultraviolet Therapy</topic><topic>Vitiligo</topic><topic>Vitiligo - epidemiology</topic><topic>Vitiligo - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xu, Wei</creatorcontrib><creatorcontrib>Qiu, Zhijin</creatorcontrib><creatorcontrib>Li, Chaolan</creatorcontrib><creatorcontrib>Wang, Yuyi</creatorcontrib><creatorcontrib>Lin, Mao</creatorcontrib><creatorcontrib>Liu, Yi</creatorcontrib><creatorcontrib>Wen, Yating</creatorcontrib><creatorcontrib>Zheng, Wenhao</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cosmetic dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xu, Wei</au><au>Qiu, Zhijin</au><au>Li, Chaolan</au><au>Wang, Yuyi</au><au>Lin, Mao</au><au>Liu, Yi</au><au>Wen, Yating</au><au>Zheng, Wenhao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recurrence and risk factors in cured patients with vitiligo: A real‐life single‐center retrospective study</atitle><jtitle>Journal of cosmetic dermatology</jtitle><addtitle>J Cosmet Dermatol</addtitle><date>2023-05</date><risdate>2023</risdate><volume>22</volume><issue>5</issue><spage>1680</spage><epage>1684</epage><pages>1680-1684</pages><issn>1473-2130</issn><eissn>1473-2165</eissn><abstract>Background
The risk of recurrence after successful repigmentation in vitiligo has attracted attention from both patients and clinicians.
Objectives
The recurrence rate and risk factors in cured patients with vitiligo were analyzed to improve clinical prevention and treatment.
Methods
Clinical records of 76 patients with vitiligo who demonstrated at least 80% repigmentation were analyzed retrospectively. Single‐factor analysis of variance and binary logistic regression analysis was employed to screen the risk factors of vitiligo recurrence.
Results
Among the 76 cured patients, 26 relapsed (total recurrence rate of 34.2%). Among these, 20 relapsed within one year (recurrence rate of 26.3%). Single‐factor analysis of variance revealed significant differences (p < 0.05) with the age of onset (yr), distribution of onset, and oral traditional Chinese medicine (TCM) intake between the recurrence and nonrecurrence groups. Binary logistic regression analysis displayed that the age of onset (yr) (p = 0.015, OR = 1.051), distribution of onset (p = 0.046, OR = 0.194), and oral TCM (p = 0.018, OR = 4.360) are significant risk factors for vitiligo recurrence.
Conclusion
A total relapse rate of 34.2% was observed in cured vitiligo patients. The age of onset (yr), distribution of onset, and oral TCM are risk factors for vitiligo recurrence. The necessary interventions should be considered on these factors for reducing the recurrence rate of vitiligo.</abstract><cop>England</cop><pub>John Wiley & Sons, Inc</pub><pmid>36721299</pmid><doi>10.1111/jocd.15637</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Wiley Online Library Open Access; Wiley Online Library Journals Frontfile Complete |
| subjects | Age Autoimmune diseases Chi-square test Chinese medicine Combined Modality Therapy Disease Family medical history Hospitals Humans Recurrence Regression analysis Retrospective Studies Risk factors Steroids Treatment Outcome Ultraviolet Therapy Vitiligo Vitiligo - epidemiology Vitiligo - therapy |
| title | Recurrence and risk factors in cured patients with vitiligo: A real‐life single‐center retrospective study |
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