Evaluation of the oxidative toxicity induced by lead, manganese, and cadmium using genetically modified nrf2a-mutant zebrafish

Heavy metal pollution has become a serious environmental concern and a threat to public health. Three of the most common heavy metals are cadmium (Cd), lead (Pb), and manganese (Mn). Nuclear factor erythroid 2–related factor 2 (Nrf2) is an important transcription factor activated in the response to...

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Veröffentlicht in:	Comparative biochemistry and physiology. Toxicology & pharmacology 2023-04, Vol.266, p.109550-109550, Article 109550
Hauptverfasser:	Xu, Yongjie, Peng, Tao, Zhou, Qin, Zhu, Jiawei, Liao, Gengze, Zou, Fei, Meng, Xiaojing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cadmium Cadmium - metabolism Cadmium - toxicity CRISPR/Cas9 Lead Lead - toxicity Manganese Manganese - toxicity Metals, Heavy - toxicity Oxidative Stress Oxidative toxicity Zebrafish Zebrafish - genetics Zebrafish - metabolism
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