Transcription Factor Nrf2 and Mitochondria – Friends or Foes in the Regulation of Aging Rate

At the first sight, the transcription factor Nrf2 as a master regulator of cellular antioxidant systems, and mitochondria as the main source of reactive oxygen species (ROS), should play the opposite roles in determining the pace of aging. However, since the causes of aging cannot be confined to the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Moscow) 2022-12, Vol.87 (12-13), p.1477-1486
Hauptverfasser:	Shilovsky, Gregory A., Ashapkin, Vasily V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Analysis Antioxidants Antioxidants - metabolism Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Electron transport Genomes Genomics Homeostasis Humans Identification and classification Life Sciences Life span Metabolites Microbiology Mitochondria Mitochondria - metabolism Mitochondrial DNA Molecular modelling NF-E2-Related Factor 2 - metabolism Oxidative stress Oxidative Stress - physiology Peptides Properties Proteins Quality control Reactive oxygen species Reactive Oxygen Species - metabolism Regulation Regulatory proteins Review Signal peptides Transcription factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!