Antimetabolite in the Management of Odontogenic Keratocyst-A Case Report

Antimetabolite in the Management of Odontogenic Keratocyst-A Case Report

Odontogenic keratocyst (OKC) is an aggressive cystic lesion of the jaw with high growth and recurrence. Patients are usually asymptomatic and detected during routine radiographic examination. Management of OKC varies from conservative procedures like simple Enucleation and peripheral ostectomy to ag...

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Veröffentlicht in:Journal of maxillofacial and oral surgery 2023, Vol.22 (1), p.132-135
Hauptverfasser: Banala, Poojitha, Reddy, G Santhosh, Harish Kumar, T V S, Bhavani, M
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container_title Journal of maxillofacial and oral surgery
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creator Banala, Poojitha
Reddy, G Santhosh
Harish Kumar, T V S
Bhavani, M
description Odontogenic keratocyst (OKC) is an aggressive cystic lesion of the jaw with high growth and recurrence. Patients are usually asymptomatic and detected during routine radiographic examination. Management of OKC varies from conservative procedures like simple Enucleation and peripheral ostectomy to aggressive resection. More attention is given to new treatment protocols to form them simple and successful. 5 fluorouracil is an anti-metabolite used to treat basal cell carcinoma and other malignancies act by inhibiting thymidylate synthase an enzyme required for DNA synthesis causing cell death. This is a case report of a 40-year-old female patient with OKC treated with topical 5 fluorouracil after enucleation, has less morbidity minimal recurrence, and low cost.
doi_str_mv 10.1007/s12663-022-01751-0
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title Antimetabolite in the Management of Odontogenic Keratocyst-A Case Report
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