How do antimicrobial peptides disrupt the lipopolysaccharide membrane leaflet of Gram-negative bacteria?

[Display omitted] It is widely regarded that antimicrobial peptides (AMPs) kill bacteria by physically disrupting microbial membranes and causing cytoplasmic leakage, but it remains unclear how AMPs disrupt the outer membrane (OM) of Gram-negative bacteria (GNB) and then compromise the inner membran...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of colloid and interface science 2023-05, Vol.637, p.182-192
Hauptverfasser:	Gong, Haoning, Hu, Xuzhi, Zhang, Lin, Fa, Ke, Liao, Mingrui, Liu, Huayang, Fragneto, Giovanna, Campana, Mario, Lu, Jian Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-infection Anti-Infective Agents - chemistry Antimicrobial peptide Antimicrobial Peptides Bacteria - metabolism Cell Membrane - metabolism Escherichia coli - metabolism Gram-Negative Bacteria - metabolism Lipopolysaccharide Lipopolysaccharides - chemistry Lipopolysaccharides - pharmacology Melitten - metabolism Melitten - pharmacology Neutron reflection Structural disruption
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!