Facile synthesis, crystal structure, quantum calculation, and biological evaluations of novel selenenyl sulfide compounds as potential agrochemicals

BACKGROUND In order to design compounds with fresh molecular skeleton to break through the limitation of available agrochemicals, a series of 36 novel selenenyl sulfide compounds were chemically synthesized, and their biological activities were fully evaluated against tobacco mosaic virus (TMV), 14...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pest management science 2023-05, Vol.79 (5), p.1885-1896
Hauptverfasser: Shang, Ming‐Hao, Sun, Xue‐Wen, Wang, Hai‐Lian, Li, Hao‐Ran, Zhang, Jia‐Shuang, Wang, Li‐Zhong, Yu, Shu‐Jing, Zhang, Xiao, Xiong, LI‐Xia, Li, Yong‐Hong, Niu, Cong‐Wei, Wang, Jian‐Guo
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1896
container_issue 5
container_start_page 1885
container_title Pest management science
container_volume 79
creator Shang, Ming‐Hao
Sun, Xue‐Wen
Wang, Hai‐Lian
Li, Hao‐Ran
Zhang, Jia‐Shuang
Wang, Li‐Zhong
Yu, Shu‐Jing
Zhang, Xiao
Xiong, LI‐Xia
Li, Yong‐Hong
Niu, Cong‐Wei
Wang, Jian‐Guo
description BACKGROUND In order to design compounds with fresh molecular skeleton to break through the limitation of available agrochemicals, a series of 36 novel selenenyl sulfide compounds were chemically synthesized, and their biological activities were fully evaluated against tobacco mosaic virus (TMV), 14 plant pathogenic fungi, three insect species and plant acetohydroxyacid synthase (AHAS). RESULTS All the target compounds were characterized by proton nuclear magnetic resonance (1H‐NMR), carbon‐13 (13C)‐NMR, selenium‐77 (77Se)‐NMR, and high‐resolution mass spectrometry (HRMS). The crystal structure of 10j indicated that the Se–S bond was successfully constructed. Compounds 10d, 10h, 10s, 10u, 10aa, 10ac, 10ae, 10ag, and 10ai exhibited 40%, 43%, 39%, 41%, 47%, 46%, 47%, 42%, and 39% anti‐TMV activities at 500 mg L−1, better than that of ribavirin. The median effective concentration (EC50) against Sclerotinia sclerotiorum of 10ac was 6.69 mg L−1 and EC50 values against Physalospora piricola and Pyricularia grisea of 10z were 12.25 mg L−1 and 15.27 mg L−1, respectively, superior to the corresponding values of chlorothalonil. Compounds 10c and 10v demonstrated 100% larvicidal activity against Culex pipiens pallens at 5 mg L−1, while 10a displayed 100% insecticidal activity against Mythimna separata at 200 mg L−1. Compounds 10c, 10j, and 10o showed > 60% inhibitions against plant AHAS at 10 μmol L−1. From the quantum calculation, highest occupied molecular orbital (HOMO) was considered as a factor that affects the anti‐TMV activity. CONCLUSION The preliminary results suggested that more efforts should be devoted to exploring the selenenyl sulfides for the discovery of new leads of antiviral agent, fungicide, insecticide or AHAS inhibitors as potential agrochemicals for crop protection. © 2023 Society of Chemical Industry. A series of novel selenenyl sulfide compounds were chemically synthesized and the biological activities were evaluated for the discovery of novel agrochemicals with new chemical skeleton.
doi_str_mv 10.1002/ps.7382
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2769997827</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2769997827</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3452-93d7690cbd21f063d480f0ad0d71609806c2c8876b8aa31414ec74ff2cdbc3913</originalsourceid><addsrcrecordid>eNp1kd9qFTEQhxdRbK3iG0jACwXPqfmz3U0uS7EqFBRU8G7JJrNtSjbZZpLKvocPbE5P7YXg1Qwz33yE_JrmJaPHjFL-fsHjXkj-qDlkJ7zbtkrJxw-9_HnQPEO8ppQqpfjT5kB0fb2S8rD5fa6N80BwDfkK0OGGmLRi1p5gTsXkkmBDbooOuczEaG-K19nFsCE6WDK66OOlq3MCt9qXuxWSOJEQb6E6wEOAsNau-MlZICbOSyzBItFIlpghZFev9WWK5grmnQqfN0-mWuDFfT1qfpx_-H72aXvx5ePns9OLrRHtCd8qYftOUTNazibaCdtKOlFtqe1ZR5WkneFGyr4bpdaCtawF07fTxI0djVBMHDVv994lxZsCmIfZoQHvdYBYcOBVr1QveV_R1_-g17GkUF9XKSVE_X3BK_VmT5kUERNMw5LcrNM6MDrsghoWHHZBVfLVva-MM9gH7m8yFXi3B37VeNb_eYav3-50fwD5qp6b</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2793373832</pqid></control><display><type>article</type><title>Facile synthesis, crystal structure, quantum calculation, and biological evaluations of novel selenenyl sulfide compounds as potential agrochemicals</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Shang, Ming‐Hao ; Sun, Xue‐Wen ; Wang, Hai‐Lian ; Li, Hao‐Ran ; Zhang, Jia‐Shuang ; Wang, Li‐Zhong ; Yu, Shu‐Jing ; Zhang, Xiao ; Xiong, LI‐Xia ; Li, Yong‐Hong ; Niu, Cong‐Wei ; Wang, Jian‐Guo</creator><creatorcontrib>Shang, Ming‐Hao ; Sun, Xue‐Wen ; Wang, Hai‐Lian ; Li, Hao‐Ran ; Zhang, Jia‐Shuang ; Wang, Li‐Zhong ; Yu, Shu‐Jing ; Zhang, Xiao ; Xiong, LI‐Xia ; Li, Yong‐Hong ; Niu, Cong‐Wei ; Wang, Jian‐Guo</creatorcontrib><description>BACKGROUND In order to design compounds with fresh molecular skeleton to break through the limitation of available agrochemicals, a series of 36 novel selenenyl sulfide compounds were chemically synthesized, and their biological activities were fully evaluated against tobacco mosaic virus (TMV), 14 plant pathogenic fungi, three insect species and plant acetohydroxyacid synthase (AHAS). RESULTS All the target compounds were characterized by proton nuclear magnetic resonance (1H‐NMR), carbon‐13 (13C)‐NMR, selenium‐77 (77Se)‐NMR, and high‐resolution mass spectrometry (HRMS). The crystal structure of 10j indicated that the Se–S bond was successfully constructed. Compounds 10d, 10h, 10s, 10u, 10aa, 10ac, 10ae, 10ag, and 10ai exhibited 40%, 43%, 39%, 41%, 47%, 46%, 47%, 42%, and 39% anti‐TMV activities at 500 mg L−1, better than that of ribavirin. The median effective concentration (EC50) against Sclerotinia sclerotiorum of 10ac was 6.69 mg L−1 and EC50 values against Physalospora piricola and Pyricularia grisea of 10z were 12.25 mg L−1 and 15.27 mg L−1, respectively, superior to the corresponding values of chlorothalonil. Compounds 10c and 10v demonstrated 100% larvicidal activity against Culex pipiens pallens at 5 mg L−1, while 10a displayed 100% insecticidal activity against Mythimna separata at 200 mg L−1. Compounds 10c, 10j, and 10o showed &gt; 60% inhibitions against plant AHAS at 10 μmol L−1. From the quantum calculation, highest occupied molecular orbital (HOMO) was considered as a factor that affects the anti‐TMV activity. CONCLUSION The preliminary results suggested that more efforts should be devoted to exploring the selenenyl sulfides for the discovery of new leads of antiviral agent, fungicide, insecticide or AHAS inhibitors as potential agrochemicals for crop protection. © 2023 Society of Chemical Industry. A series of novel selenenyl sulfide compounds were chemically synthesized and the biological activities were evaluated for the discovery of novel agrochemicals with new chemical skeleton.</description><identifier>ISSN: 1526-498X</identifier><identifier>EISSN: 1526-4998</identifier><identifier>DOI: 10.1002/ps.7382</identifier><identifier>PMID: 36700288</identifier><language>eng</language><publisher>Chichester, UK: John Wiley &amp; Sons, Ltd</publisher><subject>Acetohydroxyacid synthase ; Agrochemicals ; AHAS inhibition ; Animals ; antifungal activity ; antiviral activity ; Antiviral Agents ; Chlorothalonil ; Crystal structure ; Drug Design ; Fungicides ; Fungicides, Industrial - chemistry ; Insecticides ; Insecticides - chemistry ; Insects ; larvicidal activity ; Mass spectrometry ; Mass spectroscopy ; Mathematical analysis ; Molecular orbitals ; Molecular Structure ; Moths ; NMR ; Nuclear magnetic resonance ; Plant protection ; Ribavirin ; selenenyl sulfide ; Selenium ; Structure-Activity Relationship ; Sulfide compounds ; Sulfides ; Sulfides - pharmacology ; Tobacco ; Tobacco Mosaic Virus ; Viruses</subject><ispartof>Pest management science, 2023-05, Vol.79 (5), p.1885-1896</ispartof><rights>2023 Society of Chemical Industry.</rights><rights>Copyright © 2023 Society of Chemical Industry</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3452-93d7690cbd21f063d480f0ad0d71609806c2c8876b8aa31414ec74ff2cdbc3913</citedby><cites>FETCH-LOGICAL-c3452-93d7690cbd21f063d480f0ad0d71609806c2c8876b8aa31414ec74ff2cdbc3913</cites><orcidid>0000-0001-7577-1502 ; 0000-0003-4754-1245</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fps.7382$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fps.7382$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36700288$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shang, Ming‐Hao</creatorcontrib><creatorcontrib>Sun, Xue‐Wen</creatorcontrib><creatorcontrib>Wang, Hai‐Lian</creatorcontrib><creatorcontrib>Li, Hao‐Ran</creatorcontrib><creatorcontrib>Zhang, Jia‐Shuang</creatorcontrib><creatorcontrib>Wang, Li‐Zhong</creatorcontrib><creatorcontrib>Yu, Shu‐Jing</creatorcontrib><creatorcontrib>Zhang, Xiao</creatorcontrib><creatorcontrib>Xiong, LI‐Xia</creatorcontrib><creatorcontrib>Li, Yong‐Hong</creatorcontrib><creatorcontrib>Niu, Cong‐Wei</creatorcontrib><creatorcontrib>Wang, Jian‐Guo</creatorcontrib><title>Facile synthesis, crystal structure, quantum calculation, and biological evaluations of novel selenenyl sulfide compounds as potential agrochemicals</title><title>Pest management science</title><addtitle>Pest Manag Sci</addtitle><description>BACKGROUND In order to design compounds with fresh molecular skeleton to break through the limitation of available agrochemicals, a series of 36 novel selenenyl sulfide compounds were chemically synthesized, and their biological activities were fully evaluated against tobacco mosaic virus (TMV), 14 plant pathogenic fungi, three insect species and plant acetohydroxyacid synthase (AHAS). RESULTS All the target compounds were characterized by proton nuclear magnetic resonance (1H‐NMR), carbon‐13 (13C)‐NMR, selenium‐77 (77Se)‐NMR, and high‐resolution mass spectrometry (HRMS). The crystal structure of 10j indicated that the Se–S bond was successfully constructed. Compounds 10d, 10h, 10s, 10u, 10aa, 10ac, 10ae, 10ag, and 10ai exhibited 40%, 43%, 39%, 41%, 47%, 46%, 47%, 42%, and 39% anti‐TMV activities at 500 mg L−1, better than that of ribavirin. The median effective concentration (EC50) against Sclerotinia sclerotiorum of 10ac was 6.69 mg L−1 and EC50 values against Physalospora piricola and Pyricularia grisea of 10z were 12.25 mg L−1 and 15.27 mg L−1, respectively, superior to the corresponding values of chlorothalonil. Compounds 10c and 10v demonstrated 100% larvicidal activity against Culex pipiens pallens at 5 mg L−1, while 10a displayed 100% insecticidal activity against Mythimna separata at 200 mg L−1. Compounds 10c, 10j, and 10o showed &gt; 60% inhibitions against plant AHAS at 10 μmol L−1. From the quantum calculation, highest occupied molecular orbital (HOMO) was considered as a factor that affects the anti‐TMV activity. CONCLUSION The preliminary results suggested that more efforts should be devoted to exploring the selenenyl sulfides for the discovery of new leads of antiviral agent, fungicide, insecticide or AHAS inhibitors as potential agrochemicals for crop protection. © 2023 Society of Chemical Industry. A series of novel selenenyl sulfide compounds were chemically synthesized and the biological activities were evaluated for the discovery of novel agrochemicals with new chemical skeleton.</description><subject>Acetohydroxyacid synthase</subject><subject>Agrochemicals</subject><subject>AHAS inhibition</subject><subject>Animals</subject><subject>antifungal activity</subject><subject>antiviral activity</subject><subject>Antiviral Agents</subject><subject>Chlorothalonil</subject><subject>Crystal structure</subject><subject>Drug Design</subject><subject>Fungicides</subject><subject>Fungicides, Industrial - chemistry</subject><subject>Insecticides</subject><subject>Insecticides - chemistry</subject><subject>Insects</subject><subject>larvicidal activity</subject><subject>Mass spectrometry</subject><subject>Mass spectroscopy</subject><subject>Mathematical analysis</subject><subject>Molecular orbitals</subject><subject>Molecular Structure</subject><subject>Moths</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Plant protection</subject><subject>Ribavirin</subject><subject>selenenyl sulfide</subject><subject>Selenium</subject><subject>Structure-Activity Relationship</subject><subject>Sulfide compounds</subject><subject>Sulfides</subject><subject>Sulfides - pharmacology</subject><subject>Tobacco</subject><subject>Tobacco Mosaic Virus</subject><subject>Viruses</subject><issn>1526-498X</issn><issn>1526-4998</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kd9qFTEQhxdRbK3iG0jACwXPqfmz3U0uS7EqFBRU8G7JJrNtSjbZZpLKvocPbE5P7YXg1Qwz33yE_JrmJaPHjFL-fsHjXkj-qDlkJ7zbtkrJxw-9_HnQPEO8ppQqpfjT5kB0fb2S8rD5fa6N80BwDfkK0OGGmLRi1p5gTsXkkmBDbooOuczEaG-K19nFsCE6WDK66OOlq3MCt9qXuxWSOJEQb6E6wEOAsNau-MlZICbOSyzBItFIlpghZFev9WWK5grmnQqfN0-mWuDFfT1qfpx_-H72aXvx5ePns9OLrRHtCd8qYftOUTNazibaCdtKOlFtqe1ZR5WkneFGyr4bpdaCtawF07fTxI0djVBMHDVv994lxZsCmIfZoQHvdYBYcOBVr1QveV_R1_-g17GkUF9XKSVE_X3BK_VmT5kUERNMw5LcrNM6MDrsghoWHHZBVfLVva-MM9gH7m8yFXi3B37VeNb_eYav3-50fwD5qp6b</recordid><startdate>202305</startdate><enddate>202305</enddate><creator>Shang, Ming‐Hao</creator><creator>Sun, Xue‐Wen</creator><creator>Wang, Hai‐Lian</creator><creator>Li, Hao‐Ran</creator><creator>Zhang, Jia‐Shuang</creator><creator>Wang, Li‐Zhong</creator><creator>Yu, Shu‐Jing</creator><creator>Zhang, Xiao</creator><creator>Xiong, LI‐Xia</creator><creator>Li, Yong‐Hong</creator><creator>Niu, Cong‐Wei</creator><creator>Wang, Jian‐Guo</creator><general>John Wiley &amp; Sons, Ltd</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7SS</scope><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>SOI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7577-1502</orcidid><orcidid>https://orcid.org/0000-0003-4754-1245</orcidid></search><sort><creationdate>202305</creationdate><title>Facile synthesis, crystal structure, quantum calculation, and biological evaluations of novel selenenyl sulfide compounds as potential agrochemicals</title><author>Shang, Ming‐Hao ; Sun, Xue‐Wen ; Wang, Hai‐Lian ; Li, Hao‐Ran ; Zhang, Jia‐Shuang ; Wang, Li‐Zhong ; Yu, Shu‐Jing ; Zhang, Xiao ; Xiong, LI‐Xia ; Li, Yong‐Hong ; Niu, Cong‐Wei ; Wang, Jian‐Guo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3452-93d7690cbd21f063d480f0ad0d71609806c2c8876b8aa31414ec74ff2cdbc3913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acetohydroxyacid synthase</topic><topic>Agrochemicals</topic><topic>AHAS inhibition</topic><topic>Animals</topic><topic>antifungal activity</topic><topic>antiviral activity</topic><topic>Antiviral Agents</topic><topic>Chlorothalonil</topic><topic>Crystal structure</topic><topic>Drug Design</topic><topic>Fungicides</topic><topic>Fungicides, Industrial - chemistry</topic><topic>Insecticides</topic><topic>Insecticides - chemistry</topic><topic>Insects</topic><topic>larvicidal activity</topic><topic>Mass spectrometry</topic><topic>Mass spectroscopy</topic><topic>Mathematical analysis</topic><topic>Molecular orbitals</topic><topic>Molecular Structure</topic><topic>Moths</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Plant protection</topic><topic>Ribavirin</topic><topic>selenenyl sulfide</topic><topic>Selenium</topic><topic>Structure-Activity Relationship</topic><topic>Sulfide compounds</topic><topic>Sulfides</topic><topic>Sulfides - pharmacology</topic><topic>Tobacco</topic><topic>Tobacco Mosaic Virus</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shang, Ming‐Hao</creatorcontrib><creatorcontrib>Sun, Xue‐Wen</creatorcontrib><creatorcontrib>Wang, Hai‐Lian</creatorcontrib><creatorcontrib>Li, Hao‐Ran</creatorcontrib><creatorcontrib>Zhang, Jia‐Shuang</creatorcontrib><creatorcontrib>Wang, Li‐Zhong</creatorcontrib><creatorcontrib>Yu, Shu‐Jing</creatorcontrib><creatorcontrib>Zhang, Xiao</creatorcontrib><creatorcontrib>Xiong, LI‐Xia</creatorcontrib><creatorcontrib>Li, Yong‐Hong</creatorcontrib><creatorcontrib>Niu, Cong‐Wei</creatorcontrib><creatorcontrib>Wang, Jian‐Guo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Chemoreception Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Pest management science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shang, Ming‐Hao</au><au>Sun, Xue‐Wen</au><au>Wang, Hai‐Lian</au><au>Li, Hao‐Ran</au><au>Zhang, Jia‐Shuang</au><au>Wang, Li‐Zhong</au><au>Yu, Shu‐Jing</au><au>Zhang, Xiao</au><au>Xiong, LI‐Xia</au><au>Li, Yong‐Hong</au><au>Niu, Cong‐Wei</au><au>Wang, Jian‐Guo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Facile synthesis, crystal structure, quantum calculation, and biological evaluations of novel selenenyl sulfide compounds as potential agrochemicals</atitle><jtitle>Pest management science</jtitle><addtitle>Pest Manag Sci</addtitle><date>2023-05</date><risdate>2023</risdate><volume>79</volume><issue>5</issue><spage>1885</spage><epage>1896</epage><pages>1885-1896</pages><issn>1526-498X</issn><eissn>1526-4998</eissn><abstract>BACKGROUND In order to design compounds with fresh molecular skeleton to break through the limitation of available agrochemicals, a series of 36 novel selenenyl sulfide compounds were chemically synthesized, and their biological activities were fully evaluated against tobacco mosaic virus (TMV), 14 plant pathogenic fungi, three insect species and plant acetohydroxyacid synthase (AHAS). RESULTS All the target compounds were characterized by proton nuclear magnetic resonance (1H‐NMR), carbon‐13 (13C)‐NMR, selenium‐77 (77Se)‐NMR, and high‐resolution mass spectrometry (HRMS). The crystal structure of 10j indicated that the Se–S bond was successfully constructed. Compounds 10d, 10h, 10s, 10u, 10aa, 10ac, 10ae, 10ag, and 10ai exhibited 40%, 43%, 39%, 41%, 47%, 46%, 47%, 42%, and 39% anti‐TMV activities at 500 mg L−1, better than that of ribavirin. The median effective concentration (EC50) against Sclerotinia sclerotiorum of 10ac was 6.69 mg L−1 and EC50 values against Physalospora piricola and Pyricularia grisea of 10z were 12.25 mg L−1 and 15.27 mg L−1, respectively, superior to the corresponding values of chlorothalonil. Compounds 10c and 10v demonstrated 100% larvicidal activity against Culex pipiens pallens at 5 mg L−1, while 10a displayed 100% insecticidal activity against Mythimna separata at 200 mg L−1. Compounds 10c, 10j, and 10o showed &gt; 60% inhibitions against plant AHAS at 10 μmol L−1. From the quantum calculation, highest occupied molecular orbital (HOMO) was considered as a factor that affects the anti‐TMV activity. CONCLUSION The preliminary results suggested that more efforts should be devoted to exploring the selenenyl sulfides for the discovery of new leads of antiviral agent, fungicide, insecticide or AHAS inhibitors as potential agrochemicals for crop protection. © 2023 Society of Chemical Industry. A series of novel selenenyl sulfide compounds were chemically synthesized and the biological activities were evaluated for the discovery of novel agrochemicals with new chemical skeleton.</abstract><cop>Chichester, UK</cop><pub>John Wiley &amp; Sons, Ltd</pub><pmid>36700288</pmid><doi>10.1002/ps.7382</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0001-7577-1502</orcidid><orcidid>https://orcid.org/0000-0003-4754-1245</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1526-498X
ispartof Pest management science, 2023-05, Vol.79 (5), p.1885-1896
issn 1526-498X
1526-4998
language eng
recordid cdi_proquest_miscellaneous_2769997827
source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Acetohydroxyacid synthase
Agrochemicals
AHAS inhibition
Animals
antifungal activity
antiviral activity
Antiviral Agents
Chlorothalonil
Crystal structure
Drug Design
Fungicides
Fungicides, Industrial - chemistry
Insecticides
Insecticides - chemistry
Insects
larvicidal activity
Mass spectrometry
Mass spectroscopy
Mathematical analysis
Molecular orbitals
Molecular Structure
Moths
NMR
Nuclear magnetic resonance
Plant protection
Ribavirin
selenenyl sulfide
Selenium
Structure-Activity Relationship
Sulfide compounds
Sulfides
Sulfides - pharmacology
Tobacco
Tobacco Mosaic Virus
Viruses
title Facile synthesis, crystal structure, quantum calculation, and biological evaluations of novel selenenyl sulfide compounds as potential agrochemicals
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T03%3A26%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Facile%20synthesis,%20crystal%20structure,%20quantum%20calculation,%20and%20biological%20evaluations%20of%20novel%20selenenyl%20sulfide%20compounds%20as%20potential%20agrochemicals&rft.jtitle=Pest%20management%20science&rft.au=Shang,%20Ming%E2%80%90Hao&rft.date=2023-05&rft.volume=79&rft.issue=5&rft.spage=1885&rft.epage=1896&rft.pages=1885-1896&rft.issn=1526-498X&rft.eissn=1526-4998&rft_id=info:doi/10.1002/ps.7382&rft_dat=%3Cproquest_cross%3E2769997827%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2793373832&rft_id=info:pmid/36700288&rfr_iscdi=true