Glucagon‐like peptide‐1/glucagon receptor agonism associates with reduced metabolic adaptation and higher fat oxidation: A randomized trial

Objective This study tested the hypothesis that treatment with the glucagon‐like peptide‐1/glucagon receptor agonist SAR425899 would lead to a smaller decrease in sleeping metabolic rate (SMR; kilocalories/day) than expected from the loss of lean and fat mass (metabolic adaptation). Methods This Pha...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2023-02, Vol.31 (2), p.350-362
Hauptverfasser:	Corbin, Karen D., Carnero, Elvis A., Allerton, Timothy D., Tillner, Joachim, Bock, Christopher P., Luyet, Pierre‐Philippe, Göbel, Britta, Hall, Kevin D., Parsons, Stephanie A., Ravussin, Eric, Smith, Steven R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Body composition Energy Energy Metabolism Female Food Glucagon Glucagon-Like Peptide 1 - therapeutic use Humans Hypotheses Male Males Metabolism Nutrition research Obesity - complications Overweight - complications Overweight - drug therapy Oxidation Oxidation-Reduction Peptides Receptors, Glucagon - agonists Weight Loss
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