Comparison of the efficacy and safety of standard‐ and high‐dose daptomycin: A systematic review and meta‐analysis

Aims Standard doses of daptomycin at 4 and 6 mg/kg were used for the treatment of skin and soft tissue for infections and bacteraemia, respectively. However, increased doses of daptomycin are recommended for complicated infections by Gram‐positive organisms. Methods A systematic review was conducted...

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Veröffentlicht in:	British journal of clinical pharmacology 2023-04, Vol.89 (4), p.1291-1303
Hauptverfasser:	Samura, Masaru, Takada, Keisuke, Hirose, Naoki, Kurata, Takenori, Nagumo, Fumio, Uchida, Masaki, Inoue, Junki, Tanikawa, Koji, Enoki, Yuki, Taguchi, Kazuaki, Matsumoto, Kazuaki, Ueda, Takashi, Fujimura, Shigeru, Mikamo, Hiroshige, Takesue, Yoshio, Mitsutake, Kotaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - adverse effects Bacteremia - drug therapy daptomycin Daptomycin - adverse effects efficacy Endocarditis - chemically induced Endocarditis - complications Endocarditis - drug therapy high dose Humans meta‐analysis Osteomyelitis - chemically induced Osteomyelitis - drug therapy Retrospective Studies safety standard dose Treatment Outcome
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