Optimal Timing of Fractional CO 2 Laser on Cleft Lip Scars: A Single-Blind Randomized Controlled Cohort Study
To determine the optimal time to apply a fractional CO 2 laser for the treatment of postsecondary repair scars in patients with cleft lip. Forty-two patients with linear scarring after cleft lip repair were recruited from November 2021 to October 2022. A single-blind, randomized, controlled cohort s...
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| Veröffentlicht in: | Dermatologic surgery 2023-02, Vol.49 (2), p.145-148 |
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| container_title | Dermatologic surgery |
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| creator | Chi, Haoshu Zhao, Xinran Shen, Lingyue Liu, Yiyun Cai, Ming |
| description | To determine the optimal time to apply a fractional CO 2 laser for the treatment of postsecondary repair scars in patients with cleft lip.
Forty-two patients with linear scarring after cleft lip repair were recruited from November 2021 to October 2022. A single-blind, randomized, controlled cohort study was conducted to examine the impact of fractional CO 2 laser treatment compared with conventional conservative treatment. Thirty patients started laser treatment at 1 month ( n = 10), 3 months ( n = 10), and 6 months ( n = 10) postoperatively, and 12 patients were in the control group. Each patient was treated with high-energy low-density fractional CO 2 laser treatment 3 times at an interval of 1 month. The Vancouver Scar Scale (VSS) was used for scar evaluation to determine vascularity, pigmentation, pliability, and height.
The VSS scores decreased significantly after laser treatment ( p < .05), with the most significant improvement in scars in the group that started treatment 1 month after the surgery.
Early postoperative fractional CO 2 laser treatment of cleft lip scars is more effective than later treatment. |
| doi_str_mv | 10.1097/DSS.0000000000003688 |
| format | Article |
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Forty-two patients with linear scarring after cleft lip repair were recruited from November 2021 to October 2022. A single-blind, randomized, controlled cohort study was conducted to examine the impact of fractional CO 2 laser treatment compared with conventional conservative treatment. Thirty patients started laser treatment at 1 month ( n = 10), 3 months ( n = 10), and 6 months ( n = 10) postoperatively, and 12 patients were in the control group. Each patient was treated with high-energy low-density fractional CO 2 laser treatment 3 times at an interval of 1 month. The Vancouver Scar Scale (VSS) was used for scar evaluation to determine vascularity, pigmentation, pliability, and height.
The VSS scores decreased significantly after laser treatment ( p < .05), with the most significant improvement in scars in the group that started treatment 1 month after the surgery.
Early postoperative fractional CO 2 laser treatment of cleft lip scars is more effective than later treatment.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1097/DSS.0000000000003688</identifier><identifier>PMID: 36689573</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Cicatrix - etiology ; Cicatrix - pathology ; Cicatrix - surgery ; Cleft Lip - surgery ; Cohort Studies ; Humans ; Lasers, Gas - therapeutic use ; Single-Blind Method ; Treatment Outcome</subject><ispartof>Dermatologic surgery, 2023-02, Vol.49 (2), p.145-148</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2023 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36689573$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chi, Haoshu</creatorcontrib><creatorcontrib>Zhao, Xinran</creatorcontrib><creatorcontrib>Shen, Lingyue</creatorcontrib><creatorcontrib>Liu, Yiyun</creatorcontrib><creatorcontrib>Cai, Ming</creatorcontrib><title>Optimal Timing of Fractional CO 2 Laser on Cleft Lip Scars: A Single-Blind Randomized Controlled Cohort Study</title><title>Dermatologic surgery</title><addtitle>Dermatol Surg</addtitle><description>To determine the optimal time to apply a fractional CO 2 laser for the treatment of postsecondary repair scars in patients with cleft lip.
Forty-two patients with linear scarring after cleft lip repair were recruited from November 2021 to October 2022. A single-blind, randomized, controlled cohort study was conducted to examine the impact of fractional CO 2 laser treatment compared with conventional conservative treatment. Thirty patients started laser treatment at 1 month ( n = 10), 3 months ( n = 10), and 6 months ( n = 10) postoperatively, and 12 patients were in the control group. Each patient was treated with high-energy low-density fractional CO 2 laser treatment 3 times at an interval of 1 month. The Vancouver Scar Scale (VSS) was used for scar evaluation to determine vascularity, pigmentation, pliability, and height.
The VSS scores decreased significantly after laser treatment ( p < .05), with the most significant improvement in scars in the group that started treatment 1 month after the surgery.
Early postoperative fractional CO 2 laser treatment of cleft lip scars is more effective than later treatment.</description><subject>Cicatrix - etiology</subject><subject>Cicatrix - pathology</subject><subject>Cicatrix - surgery</subject><subject>Cleft Lip - surgery</subject><subject>Cohort Studies</subject><subject>Humans</subject><subject>Lasers, Gas - therapeutic use</subject><subject>Single-Blind Method</subject><subject>Treatment Outcome</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkUtLxTAQhYMovv-BSJZuqpNHm9Sd1idcuGB1XdIm9VbTpiYpF_311hc4mzkzfHMWZxA6InBKIBdnV2V5Cv-KZVJuoF2SUp5wQdPNWYPIEkgJ3UF7IbwAEJoz2EY7LMtkngq2i_rlGLteWfzY9d3wjF2Lb7xqYueGeVksMcULFYzHbsCFNW3Ei27EZaN8OMcXuJxvrEkubTdo_KAG7fruw2hcuCF6Z-23XDkfcRkn_X6Atlplgzn87fvo6eb6sbhLFsvb--JikYwESJZQnStVA-U1SzVjreFagGa54KAkp4SbNifAIVW6SWVaN7WRipCWCKkApGb76OTHd_TubTIhVn0XGmOtGoybQkVFljPBc8Zm9PgXnere6Gr0cxz-vfqLaAb4D7B2NhofXu20Nr5aGWXjqpqD51RQmVCgDOg8Jl_PyNgnKA53Wg</recordid><startdate>20230201</startdate><enddate>20230201</enddate><creator>Chi, Haoshu</creator><creator>Zhao, Xinran</creator><creator>Shen, Lingyue</creator><creator>Liu, Yiyun</creator><creator>Cai, Ming</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20230201</creationdate><title>Optimal Timing of Fractional CO 2 Laser on Cleft Lip Scars: A Single-Blind Randomized Controlled Cohort Study</title><author>Chi, Haoshu ; Zhao, Xinran ; Shen, Lingyue ; Liu, Yiyun ; Cai, Ming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1016-2d9aab024b35d33fe4d70d39740a84214ef910405adc585bcbe8a11f178a008d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Cicatrix - etiology</topic><topic>Cicatrix - pathology</topic><topic>Cicatrix - surgery</topic><topic>Cleft Lip - surgery</topic><topic>Cohort Studies</topic><topic>Humans</topic><topic>Lasers, Gas - therapeutic use</topic><topic>Single-Blind Method</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chi, Haoshu</creatorcontrib><creatorcontrib>Zhao, Xinran</creatorcontrib><creatorcontrib>Shen, Lingyue</creatorcontrib><creatorcontrib>Liu, Yiyun</creatorcontrib><creatorcontrib>Cai, Ming</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chi, Haoshu</au><au>Zhao, Xinran</au><au>Shen, Lingyue</au><au>Liu, Yiyun</au><au>Cai, Ming</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optimal Timing of Fractional CO 2 Laser on Cleft Lip Scars: A Single-Blind Randomized Controlled Cohort Study</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2023-02-01</date><risdate>2023</risdate><volume>49</volume><issue>2</issue><spage>145</spage><epage>148</epage><pages>145-148</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>To determine the optimal time to apply a fractional CO 2 laser for the treatment of postsecondary repair scars in patients with cleft lip.
Forty-two patients with linear scarring after cleft lip repair were recruited from November 2021 to October 2022. A single-blind, randomized, controlled cohort study was conducted to examine the impact of fractional CO 2 laser treatment compared with conventional conservative treatment. Thirty patients started laser treatment at 1 month ( n = 10), 3 months ( n = 10), and 6 months ( n = 10) postoperatively, and 12 patients were in the control group. Each patient was treated with high-energy low-density fractional CO 2 laser treatment 3 times at an interval of 1 month. The Vancouver Scar Scale (VSS) was used for scar evaluation to determine vascularity, pigmentation, pliability, and height.
The VSS scores decreased significantly after laser treatment ( p < .05), with the most significant improvement in scars in the group that started treatment 1 month after the surgery.
Early postoperative fractional CO 2 laser treatment of cleft lip scars is more effective than later treatment.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>36689573</pmid><doi>10.1097/DSS.0000000000003688</doi><tpages>4</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Cicatrix - etiology Cicatrix - pathology Cicatrix - surgery Cleft Lip - surgery Cohort Studies Humans Lasers, Gas - therapeutic use Single-Blind Method Treatment Outcome |
| title | Optimal Timing of Fractional CO 2 Laser on Cleft Lip Scars: A Single-Blind Randomized Controlled Cohort Study |
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