Procoagulant phenotype induced by oxidized high-density lipoprotein associates with acute kidney injury and death

Oxidative stress derived from severe systemic inflammation promotes conversion from high-density lipoprotein HDL to oxidized HDL (oxHDL), which interacts with vascular endothelial cells (ECs). OxHDL acquires procoagulant features playing a role in modulating coagulation, which has been linked with o...

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Veröffentlicht in:Thrombosis research 2023-03, Vol.223, p.7-23
Hauptverfasser: Prado, Yolanda, Pérez, Lorena, Eltit, Felipe, Echeverría, Cesar, Llancalahuen, Felipe M., Tapia, Pablo, González, Pablo A., Kalergis, Alexis M., Cabello-Verrugio, Claudio, Simon, Felipe
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