GPRC5B (G protein-coupled receptor class C group 5 member B) suppresses glucose starvation-induced apoptosis in head-and-neck squamous cell carcinoma

G protein-coupled receptor class C group 5 member B (GPRC5B) is involved in extracellular glucose sensing, glucose metabolism, and insulin resistance. Many cancers require glucose at high concentrations to survive and grow. We have investigated the association between tumour GPRC5B expression and th...

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Veröffentlicht in:	Biomedical Research 2023/01/25, Vol.44(1), pp.1-7
Hauptverfasser:	KANAMORI, Keisuke, OZAWA, Shigeyuki, IWABUCHI, Hiroshi, IKOMA, Takeharu, SUZUKI, Kenji, TANAKA, Kae, SAWAI, Natsuko YOSHIMURA, ABE, Takahiro, KATO, Yasumasa, HATA, Ryu-Ichiro, KOBAYASHI, Masaru
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - genetics Breast cancer Cancer Cell culture Cell Line, Tumor Cell survival Chemoreception Culture Glucose Glucose - metabolism Head & neck cancer Head and neck carcinoma Head and Neck Neoplasms - genetics Humans Insulin Insulin resistance Medical prognosis Metabolism Proteins Receptors Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - genetics Starvation Survival Tumors
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