Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells

Unveiling the principles governing embryonic stem cell (ESC) differentiation into specific lineages is critical for understanding embryonic development and for stem cell applications in regenerative medicine. Here, we establish an intersection between LIF‐Stat3 signaling that is essential for mainta...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	EMBO reports 2023-03, Vol.24 (3), p.e55683-n/a
Hauptverfasser:	Cao, Leixi, Wang, Ruijie, Liu, Guangzhi, Zhang, Yuwei, Thorne, Rick Francis, Zhang, Xu Dong, Li, Jinming, Xia, Yang, Guo, Lili, Shao, Fengmin, Gu, Hao, Wu, Mian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Biomarkers Cell differentiation Cell Differentiation - genetics Circuits Destabilization Differentiation EMBO11 EMBO31 EMBO34 Embryo cells Embryogenesis Embryonic growth stage embryonic stem cell differentiation Embryonic Stem Cells - metabolism Female Gene expression Glycolysis kinase Kinases Life Sciences LIF‐Stat3 Lin41 Mice Mouse Embryonic Stem Cells - metabolism Pfkp Phosphofructokinase Phosphofructokinases - metabolism Phosphorylation Pluripotency Pregnancy Proteasomes Protein kinase Protein Kinases - metabolism Proteins Regenerative medicine Signal Transduction Signaling Specifications Stat3 protein Stem cells Substrate specificity Substrates Wiring
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!