Smart de novo Macromolecular Structure Modeling from Cryo-EM Maps

[Display omitted] •Providing an overview of the cross disciplinary knowledge to building models in silico.•Review of the challenges in machine learning-based de novo model building methods.•Review of the machine learning modeling methods we have developed in the past decade.•Discussion on the curren...

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Veröffentlicht in:	Journal of molecular biology 2023-05, Vol.435 (9), p.167967-167967, Article 167967
Hauptverfasser:	Si, Dong, Chen, Jason, Nakamura, Andrew, Chang, Luca, Guan, Haowen
Format:	Artikel
Sprache:	eng
Schlagworte:	Artificial Intelligence Cryoelectron Microscopy - methods cryogenic electron microscopy (cryo-EM) De novo deep learning macromolecular modeling Macromolecular Substances Models, Molecular Protein Conformation Proteins - chemistry Software structural biology
Online-Zugang:	Volltext
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