Analysis of deep brain stimulation of the subthalamic nucleus (STN-DBS) in patients with monogenic PRKN and LRRK2 forms of Parkinson's disease

Deep brain stimulation of the subthalamic nucleus (STN-DBS) is the most common surgical treatment for Parkinson's disease (PD). Patient selection and genetic background can modify the response to this treatment. The objective of this study was to compare both clinical and pharmacologic response...

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Veröffentlicht in:	Parkinsonism & related disorders 2023-02, Vol.107, p.105282-105282, Article 105282
Hauptverfasser:	Prendes Fernández, P., Blázquez Estrada, M., Sol Álvarez, J., Álvarez Martínez, V., Suárez San Martín, E., García Fernández, C., Álvarez Carriles, J.C., Lozano Aragoneses, B., Saiz Ayala, A., Santamarta Liébana, E., González Álvarez, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Deep brain stimulation (DBS) Deep Brain Stimulation - methods Genetics Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - genetics Levodopa - therapeutic use LRRK Parkinson Disease - surgery Parkinson Disease - therapy Parkinson's disease (PD) PRKN Retrospective Studies Subthalamic Nucleus - surgery Treatment Outcome
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