Expression of RANKL in breast cancer tissue in patients with fibrous dysplasia/McCune-Albright syndrome

In fibrous dysplasia/McCune-Albright syndrome (FD/MAS), mosaic mutations in the GNAS gene lead to locally abnormal bone turnover. Additionally, patients with FD/MAS, particularly with thoracic lesions, have an increased risk for breast cancer. Development and progression of breast cancer has been as...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2023-04, Vol.169, p.116679-116679, Article 116679
Hauptverfasser:	Meier, M.E., Hagelstein-Rotman, M., Majoor, B.C.J., Geels, R.E.S., Appelman-Dijkstra, N.M., Bravenboer, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms Female Fibrous dysplasia Fibrous Dysplasia of Bone Fibrous Dysplasia, Polyostotic GNAS Humans Ligands McCune-Albright syndrome Mutation NF-kappa B RANKL
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