Nickel-Catalyzed Three-Component Tandem Radical Cyclization 1,5-Difunctionalization of 1,3-Enynes and Alkyl Bromide

A nickel-catalyzed three-component tandem radical cyclization reaction of aryl bromides with 1,3-enynes and aryl boric acids to construct γ-lactam-substituted allene derivatives has been described. This protocol provides lactam alkyl radicals through the free radical cyclization process, which can b...

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Veröffentlicht in:Journal of organic chemistry 2023-02, Vol.88 (3), p.1403-1410
Hauptverfasser: Li, Ming, Sun, Guo-Qing, Liu, Yu-Yu, Li, Shun-Xi, Liu, Hai-Chao, Qiu, Yi-Feng, Chen, Dong-Pin, Wang, Xi-Cun, Liang, Yong-Min, Quan, Zheng-Jun
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Sprache:eng
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