An induced thymic epithelial cell‐based high throughput screen for thymus extracellular matrix mimetics

Thymic epithelial cells (TECs) are key effectors of the thymic stroma and are critically required for T‐cell development. TECs comprise a diverse set of related but functionally distinct cell types that are scarce and difficult to isolate and handle. This has precluded TEC‐based screening assays. We...

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Veröffentlicht in:	European journal of immunology 2023-03, Vol.53 (3), p.e2249934-n/a
Hauptverfasser:	Rouse, Paul, Henderson, Timothy, Venkateswaran, Seshasailam, Sweetman, Joanna, Duffy, Cairnan, Bradley, Mark, Blackburn, C. Clare
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell culture Cell Differentiation cellular reprogramming Epithelial cells Epithelial Cells - metabolism Extracellular Matrix Fetuses Gelatin Gelatin - metabolism high throughput screening assays Humans Mesenchyme Mice Polymers Stroma Thymus Thymus Gland
Online-Zugang:	Volltext
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