One-Pot Sequential Hydroamination Protocol for N‑Heterocycle Synthesis: One Method To Access Five Different Classes of Tri-Substituted Pyridines

Tri-substituted pyridines are important scaffolds that can be found in a plethora of commercially available drugs. A one-pot general method for the selective synthesis of less explored/challenging patterns of tri-substituted pyridines is described. Hydroamination of alkynes with commercially availab...

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Veröffentlicht in:Journal of organic chemistry 2023-02, Vol.88 (3), p.1378-1384
Hauptverfasser: Verma, Vani, Schafer, Laurel L.
Format: Artikel
Sprache:eng
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