Mechanistic investigation into selective cytotoxic activities of gold nanoparticles functionalized with epidermal growth factor variants

Epidermal growth factor (EGF) gains unique selective cytotoxicity against cancer cells upon conjugation with gold nanoparticles (GNPs). We have previously developed several lysine-free EGF mutants for favorable interactions between the nanoparticle conjugates with EGF receptor (EGFR) and found one m...

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Veröffentlicht in:	Analytical sciences 2023-03, Vol.39 (3), p.395-405
Hauptverfasser:	Zhang, Aiwen, Abdellatef, Shimaa A., Nakanishi, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Chemistry Chemistry and Materials Science Clathrin - metabolism Endocytosis - physiology Epidermal Growth Factor - metabolism Gold Metal Nanoparticles Original Paper
Online-Zugang:	Volltext
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