Plasmonic Hydroxyl Radical-Driven Epoxidation of Fatty Acid Double Bonds in Nanoseconds for On-Tissue Mass-Spectrometric Analysis and Bioimaging

Lipids represent a large family of compounds with highly diverse structures that are involved in complex biological processes. A photocatalytic technique of on-tissue epoxidation of C=C double bonds has been developed for in situ mass spectrometric identification and spatial imaging of positional is...

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Veröffentlicht in:	Analytical chemistry (Washington) 2023-02, Vol.95 (8), p.3976-3985
Hauptverfasser:	Jia, Shanshan, Chang, Shao, Zhang, Lin, Gui, Zhengwei, Liu, Linhui, Ma, Zhenglan, Li, Shuyu, Huang, Xingchen, Zhong, Hongying
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animal tissues Animals Anions Biological activity Breast cancer Chemistry Electron transfer Epoxidation Fatty Acids Fatty Acids, Unsaturated - analysis Free radicals Hot electrons Hydroxyl Radical Hydroxyl radicals Ions Irradiation Isomerism Isomers Lipids Mass Spectrometry Medical imaging Mice Nanotechnology Nanowires Oxidation Plasmonics Polyunsaturated fatty acids Pulsed lasers Rare gases Spectrometry Tissue analysis
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