Circular RNA hsa_circ_0000519 contributes to angiogenesis and tumor progression in hepatocellular carcinoma through the miR-1296/E2F7 axis

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Uncontrolled angiogenesis plays a critical role in hepatocellular tumor growth and metastasis. In this study, we aimed to investigate the effects of circular RNA hsa_circ_0000519 and the potential involvement of microRNA (mi...

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Veröffentlicht in:	Human cell : official journal of Human Cell Research Society 2023-03, Vol.36 (2), p.738-751
Hauptverfasser:	Liu, Yi, Tang, Hui, Zhang, Yaling, Wang, Qian, Li, Shiying, Wang, Zhiyi, Shi, Xiaofeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Biomedical and Life Sciences Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Cell Biology Cell cycle Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - genetics Cell viability Circular RNA E2F protein E2F7 Transcription Factor - genetics E2F7 Transcription Factor - metabolism Gene Expression Regulation, Neoplastic Gynecology Hepatocellular carcinoma Humans Life Sciences Liver cancer Liver Neoplasms - genetics Liver Neoplasms - pathology Malignancy Metastases Mice MicroRNAs MicroRNAs - genetics miRNA Neovascularization, Pathologic - genetics Oncology Reproductive Medicine Research Article RNA, Circular - genetics Stem Cells Surgery Xenografts
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