Heterogeneity of cGMP signalling in tumour cells and the tumour microenvironment: Challenges and chances for cancer pharmacology and therapeutics

The second messenger cyclic guanosine monophosphate (cGMP) is an important regulator of human (patho-)physiology and has emerged as an attractive drug target. Currently, cGMP-elevating drugs are mainly used to treat cardiovascular diseases, but there is also increasing interest in exploring their po...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 2023-02, Vol.242, p.108337-108337, Article 108337
Hauptverfasser:	Stehle, Daniel, Barresi, Mariagiovanna, Schulz, Jennifer, Feil, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma Cyclic GMP - metabolism Guanylyl cyclase Humans Male Natriuretic peptide Neoplasms - drug therapy NO-GC stimulator PDE Pericyte Phosphodiesterase 5 Inhibitors Signal Transduction Sildenafil Citrate - pharmacology Tumor Microenvironment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!