Multiple CEST contrast imaging of nose-to-brain drug delivery using iohexol liposomes at 3T MRI

Image guided nose-to-brain drug delivery provides a non-invasive way to monitor drug delivered to the brain, and the intranasal administration could increase effective dose via bypassing Blood Brain Barrier (BBB). Here, we investigated the imaging of liposome-based drug delivery to the brain via int...

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Veröffentlicht in:	Journal of controlled release 2023-02, Vol.354, p.208-220
Hauptverfasser:	Law, Lok Hin, Huang, Jianpan, Xiao, Peng, Liu, Yang, Chen, Zilin, Lai, Joseph H.C., Han, Xiongqi, Cheng, Gerald W.Y., Tse, Kai-Hei, Chan, Kannie W.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	CEST MRI Iohexol Liposome Nose-to-brain drug delivery Polyethylene glycol
Online-Zugang:	Volltext
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