Cobalt Single-Atom Nanozyme Co-Administration with Ascorbic Acid Enables Redox Imbalance for Tumor Catalytic Ablation

The elevated antioxidant defense system in cancer cells can lead to resistance to treatments involving ROS. Breaking the redox balance of the cell system through a “open up the source and regulate the flow” strategy can inhibit the growth of cancer cells and thus design a cancer treatment strategy....

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Veröffentlicht in:	ACS biomaterials science & engineering 2023-02, Vol.9 (2), p.1066-1076
Hauptverfasser:	Ren, Guoyuan, Lu, Mingju, Zhao, Zhiqiang, Qin, Fengjuan, Li, Kai, Chen, Wenxing, Lin, Yuqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Antioxidants - pharmacology Applications and Health Ascorbic Acid - pharmacology Cobalt - pharmacology Glutathione - metabolism Glutathione - pharmacology Oxidation-Reduction Reactive Oxygen Species
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