Clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma
Our study sought to analyze the clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma. The current study included a total of 152 patients who suffered from hypopharyngeal cancer in our hospital from January 2019 to December 2...
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| Veröffentlicht in: | American journal of otolaryngology 2023-03, Vol.44 (2), p.103742-103742, Article 103742 |
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| container_end_page | 103742 |
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| container_issue | 2 |
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| container_title | American journal of otolaryngology |
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| creator | Zhou, Liangfa Qin, Shuanglai Zhang, Qiu Xu, Jian |
| description | Our study sought to analyze the clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma.
The current study included a total of 152 patients who suffered from hypopharyngeal cancer in our hospital from January 2019 to December 2020. Univariate/multivariate Logistic regression analyses were applied to analyze the risk factors of both central lymph nodes and thyroid metastasis in patients with hypopharyngeal cancer.
Significant differences were found in tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level and postoperative FT3 level between the thyroid metastasis group and the non-thyroid metastasis group, and between the central lymph node metastasis group and the non-central lymph node metastasis group (P |
| doi_str_mv | 10.1016/j.amjoto.2022.103742 |
| format | Article |
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The current study included a total of 152 patients who suffered from hypopharyngeal cancer in our hospital from January 2019 to December 2020. Univariate/multivariate Logistic regression analyses were applied to analyze the risk factors of both central lymph nodes and thyroid metastasis in patients with hypopharyngeal cancer.
Significant differences were found in tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level and postoperative FT3 level between the thyroid metastasis group and the non-thyroid metastasis group, and between the central lymph node metastasis group and the non-central lymph node metastasis group (P < 0.05). The multivariate logistic regression analysis showed that the risk factors of thyroid metastasis in patients with hypopharyngeal cancer were pathological stage and differentiation degree.
Patients with hypopharyngeal cancer complicated by thyroid metastasis or central lymph node metastasis may be associated with tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level, and postoperative FT3 level. Moreover, the risk factors responsible for central lymph node and thyroid metastasis in hypopharyngeal cancer patients were thought related to pathological stage and differentiation degree.</description><identifier>ISSN: 0196-0709</identifier><identifier>EISSN: 1532-818X</identifier><identifier>DOI: 10.1016/j.amjoto.2022.103742</identifier><identifier>PMID: 36610248</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Calcium ; Carcinoma, Papillary - pathology ; Central lymph node ; Humans ; Hypopharyngeal carcinoma ; Hypopharyngeal Neoplasms - surgery ; Lymph Nodes - pathology ; Lymphatic Metastasis - pathology ; Neck Dissection ; Retrospective Studies ; Risk Factors ; Thyroid metastasis ; Thyroid Neoplasms - pathology</subject><ispartof>American journal of otolaryngology, 2023-03, Vol.44 (2), p.103742-103742, Article 103742</ispartof><rights>2022 Elsevier Inc.</rights><rights>Copyright © 2022 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-f82453898e5e20ec01ddf394e8de1a9ac63f46405f303635fc86db1d05d510e03</citedby><cites>FETCH-LOGICAL-c362t-f82453898e5e20ec01ddf394e8de1a9ac63f46405f303635fc86db1d05d510e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.amjoto.2022.103742$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36610248$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhou, Liangfa</creatorcontrib><creatorcontrib>Qin, Shuanglai</creatorcontrib><creatorcontrib>Zhang, Qiu</creatorcontrib><creatorcontrib>Xu, Jian</creatorcontrib><title>Clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma</title><title>American journal of otolaryngology</title><addtitle>Am J Otolaryngol</addtitle><description>Our study sought to analyze the clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma.
The current study included a total of 152 patients who suffered from hypopharyngeal cancer in our hospital from January 2019 to December 2020. Univariate/multivariate Logistic regression analyses were applied to analyze the risk factors of both central lymph nodes and thyroid metastasis in patients with hypopharyngeal cancer.
Significant differences were found in tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level and postoperative FT3 level between the thyroid metastasis group and the non-thyroid metastasis group, and between the central lymph node metastasis group and the non-central lymph node metastasis group (P < 0.05). The multivariate logistic regression analysis showed that the risk factors of thyroid metastasis in patients with hypopharyngeal cancer were pathological stage and differentiation degree.
Patients with hypopharyngeal cancer complicated by thyroid metastasis or central lymph node metastasis may be associated with tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level, and postoperative FT3 level. Moreover, the risk factors responsible for central lymph node and thyroid metastasis in hypopharyngeal cancer patients were thought related to pathological stage and differentiation degree.</description><subject>Calcium</subject><subject>Carcinoma, Papillary - pathology</subject><subject>Central lymph node</subject><subject>Humans</subject><subject>Hypopharyngeal carcinoma</subject><subject>Hypopharyngeal Neoplasms - surgery</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis - pathology</subject><subject>Neck Dissection</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Thyroid metastasis</subject><subject>Thyroid Neoplasms - pathology</subject><issn>0196-0709</issn><issn>1532-818X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2LFDEQhoO4uOPqPxDJ0UuPlY_OpC-CDOsqLHhR8BaySbWdsbvTJhllbv70zWyvHoVAheKpepOHkFcMtgyYenvY2ukQS9xy4Ly2xE7yJ2TDWsEbzfS3p2QDrFMN7KC7JM9zPgCAkKJ9Ri6FUgy41BvyZz-GOTg7UjfYZF3BFHIJLlM7e1rvP2hfuzFlGnvqcC6psuNpWgY6R48PWBlOKQZPJyw21xMyDTNdbAmVz_R3KAMdTktcasRp_o7nNJtcmONkX5CL3o4ZXz7WK_L1w_WX_cfm9vPNp_3728YJxUvTay5boTuNLXJAB8z7XnQStUdmO-uU6KWS0PYChBJt77Tyd8xD61sGCOKKvFn3Lin-PGIuZgrZ4TjaGeMxG75TrNNSal1RuaIuxZwT9mZJYapPNwzM2b05mNW9Obs3q_s69vox4Xg3of839Fd2Bd6tANZ__gqYTHbVkEMfErpifAz_T7gHHn2Z_A</recordid><startdate>202303</startdate><enddate>202303</enddate><creator>Zhou, Liangfa</creator><creator>Qin, Shuanglai</creator><creator>Zhang, Qiu</creator><creator>Xu, Jian</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202303</creationdate><title>Clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma</title><author>Zhou, Liangfa ; Qin, Shuanglai ; Zhang, Qiu ; Xu, Jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-f82453898e5e20ec01ddf394e8de1a9ac63f46405f303635fc86db1d05d510e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Calcium</topic><topic>Carcinoma, Papillary - pathology</topic><topic>Central lymph node</topic><topic>Humans</topic><topic>Hypopharyngeal carcinoma</topic><topic>Hypopharyngeal Neoplasms - surgery</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis - pathology</topic><topic>Neck Dissection</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Thyroid metastasis</topic><topic>Thyroid Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhou, Liangfa</creatorcontrib><creatorcontrib>Qin, Shuanglai</creatorcontrib><creatorcontrib>Zhang, Qiu</creatorcontrib><creatorcontrib>Xu, Jian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of otolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhou, Liangfa</au><au>Qin, Shuanglai</au><au>Zhang, Qiu</au><au>Xu, Jian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma</atitle><jtitle>American journal of otolaryngology</jtitle><addtitle>Am J Otolaryngol</addtitle><date>2023-03</date><risdate>2023</risdate><volume>44</volume><issue>2</issue><spage>103742</spage><epage>103742</epage><pages>103742-103742</pages><artnum>103742</artnum><issn>0196-0709</issn><eissn>1532-818X</eissn><abstract>Our study sought to analyze the clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma.
The current study included a total of 152 patients who suffered from hypopharyngeal cancer in our hospital from January 2019 to December 2020. Univariate/multivariate Logistic regression analyses were applied to analyze the risk factors of both central lymph nodes and thyroid metastasis in patients with hypopharyngeal cancer.
Significant differences were found in tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level and postoperative FT3 level between the thyroid metastasis group and the non-thyroid metastasis group, and between the central lymph node metastasis group and the non-central lymph node metastasis group (P < 0.05). The multivariate logistic regression analysis showed that the risk factors of thyroid metastasis in patients with hypopharyngeal cancer were pathological stage and differentiation degree.
Patients with hypopharyngeal cancer complicated by thyroid metastasis or central lymph node metastasis may be associated with tobacco use, drinking history, PS score, site of tumor, pT and pN stage, pathological stage, differentiation degree, postoperative calcium ion level, and postoperative FT3 level. Moreover, the risk factors responsible for central lymph node and thyroid metastasis in hypopharyngeal cancer patients were thought related to pathological stage and differentiation degree.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>36610248</pmid><doi>10.1016/j.amjoto.2022.103742</doi><tpages>1</tpages></addata></record> |
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| ispartof | American journal of otolaryngology, 2023-03, Vol.44 (2), p.103742-103742, Article 103742 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Calcium Carcinoma, Papillary - pathology Central lymph node Humans Hypopharyngeal carcinoma Hypopharyngeal Neoplasms - surgery Lymph Nodes - pathology Lymphatic Metastasis - pathology Neck Dissection Retrospective Studies Risk Factors Thyroid metastasis Thyroid Neoplasms - pathology |
| title | Clinical characteristics and risk factors of central lymph node and thyroid metastasis in patients with hypopharyngeal carcinoma |
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