The Effect of α2-Adrenoreceptors Blockade on the Isolated Rat Heart during the Formation of Sympathetic Innervation

We studied the effects of the α 2 -adrenergic receptor antagonist yohimbine (10 –9 -10 –6 M) on inotropy, chronotropy, and coronary flow in the Langendorff-isolated heart from 3- and 6-week-old rats. Yohimbine affected all the studied functional parameters of the isolated heart. The force of contrac...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2022-12, Vol.174 (2), p.226-229
Hauptverfasser: Zefirov, T. L., Khisamieva, L. I., Kuptsova, A. M., Ziyatdinova, N. I., Zefirov, A. L.
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Sprache:eng
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