In situ crosslinking of a biomimetic peptide-PEG hydrogel via thermally triggered activation of factor XIII

There is a medical need for robust, biocompatible hydrogels that can be rapidly crosslinked in situ through the use of gentle and non-toxic triggers, which could be used as a surgical adhesive, a bone-inductive material, or for drug and gene delivery. The complete gelation system described here incl...

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Veröffentlicht in:Biomaterials 2002-07, Vol.23 (13), p.2703-2710
Hauptverfasser: Sanborn, Tracy J., Messersmith, Phillip B., Barron, Annelise E.
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Sprache:eng
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