Synthesis and structure–activity relationship of violaceoid D, a cytotoxic alkylated phenol isolated from Aspergillus violaceofuscus Gasperini

ABSTRACT The enantioselective synthesis of violaceoid D, a cytotoxic phenolic compound isolated from the culture broth of Aspergillus violaceofuscus Gasperini, was achieved. The total synthesis involves stereoselective construction of the stereogenic center of violaceoid D via Sharpless asymmetric d...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2023-03, Vol.87 (4), p.363-370
Hauptverfasser:	Shoji, Atsushi, Arai, Yuka, Asakawa, Ryuki, Saito, Tatsuo, Kuramochi, Kouji, Yajima, Arata
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Humans Molecular Structure Phenol Phenols - pharmacology Stereoisomerism Structure-Activity Relationship
Online-Zugang:	Volltext
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