Republication: In Vitro and Ex Vivo Analysis of Collagen Foams for Soft and Hard Tissue Regeneration
The aim of this study was the conception, production, material analysis and cytocompatibility analysis of a new collagen foam for medical applications. After the innovative production of various collagen sponges from bovine sources, the foams were analyzed ex vivo in terms of their structure (includ...
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| Veröffentlicht in: | In vivo (Athens) 2023-01, Vol.37 (1), p.320-328 |
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| container_title | In vivo (Athens) |
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| creator | Jung, Ole Barbeck, Mike Fan, L U Korte, Fabian Zhao, Cuifeng Krastev, Rumen Pantermehl, Sven Xiong, Xin |
| description | The aim of this study was the conception, production, material analysis and cytocompatibility analysis of a new collagen foam for medical applications.
After the innovative production of various collagen sponges from bovine sources, the foams were analyzed ex vivo in terms of their structure (including pore size) and in vitro in terms of cytocompatibility according to EN ISO 10993-5/-12. In vitro, the collagen foams were compared with the established biomaterials cerabone and Jason membrane. Materials cerabone and Jason membrane.
Collagen foams with different compositions were successfully produced from bovine sources. Ex vivo, the foams showed a stable and long-lasting primary structure quality with a bubble area of 1,000 to 2,000 μm
In vitro, all foams showed sufficient cytocompatibility.
Collagen sponges represent a promising material for hard and soft tissue regeneration. Future studies could focus on integrating and investigating different additives in the foams. |
| doi_str_mv | 10.21873/invivo.13082 |
| format | Article |
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After the innovative production of various collagen sponges from bovine sources, the foams were analyzed ex vivo in terms of their structure (including pore size) and in vitro in terms of cytocompatibility according to EN ISO 10993-5/-12. In vitro, the collagen foams were compared with the established biomaterials cerabone and Jason membrane. Materials cerabone and Jason membrane.
Collagen foams with different compositions were successfully produced from bovine sources. Ex vivo, the foams showed a stable and long-lasting primary structure quality with a bubble area of 1,000 to 2,000 μm
In vitro, all foams showed sufficient cytocompatibility.
Collagen sponges represent a promising material for hard and soft tissue regeneration. Future studies could focus on integrating and investigating different additives in the foams.</description><identifier>ISSN: 0258-851X</identifier><identifier>EISSN: 1791-7549</identifier><identifier>DOI: 10.21873/invivo.13082</identifier><identifier>PMID: 36593025</identifier><language>eng</language><publisher>Greece</publisher><subject>Animals ; Biocompatible Materials ; Cattle ; Collagen ; Hydroxyapatites</subject><ispartof>In vivo (Athens), 2023-01, Vol.37 (1), p.320-328</ispartof><rights>Copyright © 2023, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c293t-5474fed3826c82d8e9fd6807a82f26de7a9cbce315df842d99c13af7c4d0e1093</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36593025$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jung, Ole</creatorcontrib><creatorcontrib>Barbeck, Mike</creatorcontrib><creatorcontrib>Fan, L U</creatorcontrib><creatorcontrib>Korte, Fabian</creatorcontrib><creatorcontrib>Zhao, Cuifeng</creatorcontrib><creatorcontrib>Krastev, Rumen</creatorcontrib><creatorcontrib>Pantermehl, Sven</creatorcontrib><creatorcontrib>Xiong, Xin</creatorcontrib><title>Republication: In Vitro and Ex Vivo Analysis of Collagen Foams for Soft and Hard Tissue Regeneration</title><title>In vivo (Athens)</title><addtitle>In Vivo</addtitle><description>The aim of this study was the conception, production, material analysis and cytocompatibility analysis of a new collagen foam for medical applications.
After the innovative production of various collagen sponges from bovine sources, the foams were analyzed ex vivo in terms of their structure (including pore size) and in vitro in terms of cytocompatibility according to EN ISO 10993-5/-12. In vitro, the collagen foams were compared with the established biomaterials cerabone and Jason membrane. Materials cerabone and Jason membrane.
Collagen foams with different compositions were successfully produced from bovine sources. Ex vivo, the foams showed a stable and long-lasting primary structure quality with a bubble area of 1,000 to 2,000 μm
In vitro, all foams showed sufficient cytocompatibility.
Collagen sponges represent a promising material for hard and soft tissue regeneration. Future studies could focus on integrating and investigating different additives in the foams.</description><subject>Animals</subject><subject>Biocompatible Materials</subject><subject>Cattle</subject><subject>Collagen</subject><subject>Hydroxyapatites</subject><issn>0258-851X</issn><issn>1791-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1LAzEQhoMotlaPXiVHL1vzsbtJvEmxtlAQahVvS5pMJLLd1GS36L93aaun4WUe3hkehK4pGTMqBb_zzc7vwphyItkJGlKhaCaKXJ2iIWGFzGRB3wfoIqVPQkpBCDtHA14WivfbIbJL2Hbr2hvd-tDc43mD33wbA9aNxY_ffdgF_NDo-if5hIPDk1DX-gMaPA16k7ALEb8E1-75mY4Wr3xKHeAl9BDEfe0lOnO6TnB1nCP0On1cTWbZ4vlpPnlYZIYp3mZFLnIHlktWGsmsBOVsKYnQkjlWWhBambUBTgvrZM6sUoZy7YTJLQFKFB-h20PvNoavDlJbbXwy0D_cQOhSxURJ-iM0Fz2aHVATQ0oRXLWNfqPjT0VJtRdbHcRWe7E9f3Os7tYbsP_0n0n-C5ardVk</recordid><startdate>202301</startdate><enddate>202301</enddate><creator>Jung, Ole</creator><creator>Barbeck, Mike</creator><creator>Fan, L U</creator><creator>Korte, Fabian</creator><creator>Zhao, Cuifeng</creator><creator>Krastev, Rumen</creator><creator>Pantermehl, Sven</creator><creator>Xiong, Xin</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202301</creationdate><title>Republication: In Vitro and Ex Vivo Analysis of Collagen Foams for Soft and Hard Tissue Regeneration</title><author>Jung, Ole ; Barbeck, Mike ; Fan, L U ; Korte, Fabian ; Zhao, Cuifeng ; Krastev, Rumen ; Pantermehl, Sven ; Xiong, Xin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-5474fed3826c82d8e9fd6807a82f26de7a9cbce315df842d99c13af7c4d0e1093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Animals</topic><topic>Biocompatible Materials</topic><topic>Cattle</topic><topic>Collagen</topic><topic>Hydroxyapatites</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jung, Ole</creatorcontrib><creatorcontrib>Barbeck, Mike</creatorcontrib><creatorcontrib>Fan, L U</creatorcontrib><creatorcontrib>Korte, Fabian</creatorcontrib><creatorcontrib>Zhao, Cuifeng</creatorcontrib><creatorcontrib>Krastev, Rumen</creatorcontrib><creatorcontrib>Pantermehl, Sven</creatorcontrib><creatorcontrib>Xiong, Xin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>In vivo (Athens)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jung, Ole</au><au>Barbeck, Mike</au><au>Fan, L U</au><au>Korte, Fabian</au><au>Zhao, Cuifeng</au><au>Krastev, Rumen</au><au>Pantermehl, Sven</au><au>Xiong, Xin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Republication: In Vitro and Ex Vivo Analysis of Collagen Foams for Soft and Hard Tissue Regeneration</atitle><jtitle>In vivo (Athens)</jtitle><addtitle>In Vivo</addtitle><date>2023-01</date><risdate>2023</risdate><volume>37</volume><issue>1</issue><spage>320</spage><epage>328</epage><pages>320-328</pages><issn>0258-851X</issn><eissn>1791-7549</eissn><abstract>The aim of this study was the conception, production, material analysis and cytocompatibility analysis of a new collagen foam for medical applications.
After the innovative production of various collagen sponges from bovine sources, the foams were analyzed ex vivo in terms of their structure (including pore size) and in vitro in terms of cytocompatibility according to EN ISO 10993-5/-12. In vitro, the collagen foams were compared with the established biomaterials cerabone and Jason membrane. Materials cerabone and Jason membrane.
Collagen foams with different compositions were successfully produced from bovine sources. Ex vivo, the foams showed a stable and long-lasting primary structure quality with a bubble area of 1,000 to 2,000 μm
In vitro, all foams showed sufficient cytocompatibility.
Collagen sponges represent a promising material for hard and soft tissue regeneration. Future studies could focus on integrating and investigating different additives in the foams.</abstract><cop>Greece</cop><pmid>36593025</pmid><doi>10.21873/invivo.13082</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | In vivo (Athens), 2023-01, Vol.37 (1), p.320-328 |
| issn | 0258-851X 1791-7549 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Animals Biocompatible Materials Cattle Collagen Hydroxyapatites |
| title | Republication: In Vitro and Ex Vivo Analysis of Collagen Foams for Soft and Hard Tissue Regeneration |
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