A review on taste masked multiparticulate dosage forms for paediatric
[Display omitted] Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the...
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| Veröffentlicht in: | International journal of pharmaceutics 2023-02, Vol.632, p.122571-122571, Article 122571 |
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| container_title | International journal of pharmaceutics |
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| creator | AL-Japairai, Khater Hamed Almurisi, Samah Almonem Doolaanea, Abd Mahmood, Syed Alheibshy, Fawaz Alobaida, Ahmed Abdul-Halim, Nadiya Chatterjee, Bappaditya |
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Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous contributing components such as swallowability, palatability (taste, flavour, texture, and mouthfeel), appearance, ease of administration, and patient characteristics. Multiparticulate as a dosage form is a platform technology for overcoming paediatrics' incapacity to swallow monolithic dosage forms, masking many medications' inherent nasty taste, and overcoming the obstacles of manufacturing a commercially taste masked dosage form. This review will discuss the considerations that must be taken into account to prepare taste masked multiparticulate dosage forms in the best way for paediatric use. |
| doi_str_mv | 10.1016/j.ijpharm.2022.122571 |
| format | Article |
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Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous contributing components such as swallowability, palatability (taste, flavour, texture, and mouthfeel), appearance, ease of administration, and patient characteristics. Multiparticulate as a dosage form is a platform technology for overcoming paediatrics' incapacity to swallow monolithic dosage forms, masking many medications' inherent nasty taste, and overcoming the obstacles of manufacturing a commercially taste masked dosage form. This review will discuss the considerations that must be taken into account to prepare taste masked multiparticulate dosage forms in the best way for paediatric use.</description><identifier>ISSN: 0378-5173</identifier><identifier>EISSN: 1873-3476</identifier><identifier>DOI: 10.1016/j.ijpharm.2022.122571</identifier><identifier>PMID: 36587776</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Administration, Oral ; Chemistry, Pharmaceutical ; Child ; Dosage Forms ; Humans ; Multiparticulate system ; Paediatric ; Pediatrics ; Pharmaceutical Preparations ; Taste ; Taste masking ; Taste Perception ; Unpleasant drug</subject><ispartof>International journal of pharmaceutics, 2023-02, Vol.632, p.122571-122571, Article 122571</ispartof><rights>2022 Elsevier B.V.</rights><rights>Copyright © 2022 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-d6ae04467fd12a152c758c833488863e71656f506d56559e170f7aac1ccd575c3</citedby><cites>FETCH-LOGICAL-c365t-d6ae04467fd12a152c758c833488863e71656f506d56559e170f7aac1ccd575c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0378517322011267$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36587776$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>AL-Japairai, Khater</creatorcontrib><creatorcontrib>Hamed Almurisi, Samah</creatorcontrib><creatorcontrib>Almonem Doolaanea, Abd</creatorcontrib><creatorcontrib>Mahmood, Syed</creatorcontrib><creatorcontrib>Alheibshy, Fawaz</creatorcontrib><creatorcontrib>Alobaida, Ahmed</creatorcontrib><creatorcontrib>Abdul-Halim, Nadiya</creatorcontrib><creatorcontrib>Chatterjee, Bappaditya</creatorcontrib><title>A review on taste masked multiparticulate dosage forms for paediatric</title><title>International journal of pharmaceutics</title><addtitle>Int J Pharm</addtitle><description>[Display omitted]
Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous contributing components such as swallowability, palatability (taste, flavour, texture, and mouthfeel), appearance, ease of administration, and patient characteristics. Multiparticulate as a dosage form is a platform technology for overcoming paediatrics' incapacity to swallow monolithic dosage forms, masking many medications' inherent nasty taste, and overcoming the obstacles of manufacturing a commercially taste masked dosage form. This review will discuss the considerations that must be taken into account to prepare taste masked multiparticulate dosage forms in the best way for paediatric use.</description><subject>Administration, Oral</subject><subject>Chemistry, Pharmaceutical</subject><subject>Child</subject><subject>Dosage Forms</subject><subject>Humans</subject><subject>Multiparticulate system</subject><subject>Paediatric</subject><subject>Pediatrics</subject><subject>Pharmaceutical Preparations</subject><subject>Taste</subject><subject>Taste masking</subject><subject>Taste Perception</subject><subject>Unpleasant drug</subject><issn>0378-5173</issn><issn>1873-3476</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EoqXwCaAs2ST4ET9YoaoqD6kSG1hbxp6AQ9IE2wHx96RKYctmRhqdmas5CJ0TXBBMxFVd-Lp_M6EtKKa0IJRySQ7QnCjJclZKcYjmmEmVcyLZDJ3EWGOMBSXsGM2Y4EpKKeZovcwCfHr4yrptlkxMkLUmvoPL2qFJvjcheTs0Zpy7LppXyKoutHFXs96A8yYFb0_RUWWaCGf7vkDPt-un1X2-ebx7WC03uR0TU-6EAVyWQlaOUEM4tZIrqxgrlVKCgSSCi4pj4bjg_BqIxJU0xhJrHZfcsgW6nO72ofsYICbd-mihacwWuiFqKgUmkrKSjiifUBu6GANUug--NeFbE6x3BnWt9wb1zqCeDI57F_uI4aUF97f1q2wEbiYAxkdHc0FH62FrRxcBbNKu8_9E_AAPqYO5</recordid><startdate>20230205</startdate><enddate>20230205</enddate><creator>AL-Japairai, Khater</creator><creator>Hamed Almurisi, Samah</creator><creator>Almonem Doolaanea, Abd</creator><creator>Mahmood, Syed</creator><creator>Alheibshy, Fawaz</creator><creator>Alobaida, Ahmed</creator><creator>Abdul-Halim, Nadiya</creator><creator>Chatterjee, Bappaditya</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20230205</creationdate><title>A review on taste masked multiparticulate dosage forms for paediatric</title><author>AL-Japairai, Khater ; Hamed Almurisi, Samah ; Almonem Doolaanea, Abd ; Mahmood, Syed ; Alheibshy, Fawaz ; Alobaida, Ahmed ; Abdul-Halim, Nadiya ; Chatterjee, Bappaditya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-d6ae04467fd12a152c758c833488863e71656f506d56559e170f7aac1ccd575c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Administration, Oral</topic><topic>Chemistry, Pharmaceutical</topic><topic>Child</topic><topic>Dosage Forms</topic><topic>Humans</topic><topic>Multiparticulate system</topic><topic>Paediatric</topic><topic>Pediatrics</topic><topic>Pharmaceutical Preparations</topic><topic>Taste</topic><topic>Taste masking</topic><topic>Taste Perception</topic><topic>Unpleasant drug</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AL-Japairai, Khater</creatorcontrib><creatorcontrib>Hamed Almurisi, Samah</creatorcontrib><creatorcontrib>Almonem Doolaanea, Abd</creatorcontrib><creatorcontrib>Mahmood, Syed</creatorcontrib><creatorcontrib>Alheibshy, Fawaz</creatorcontrib><creatorcontrib>Alobaida, Ahmed</creatorcontrib><creatorcontrib>Abdul-Halim, Nadiya</creatorcontrib><creatorcontrib>Chatterjee, Bappaditya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of pharmaceutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AL-Japairai, Khater</au><au>Hamed Almurisi, Samah</au><au>Almonem Doolaanea, Abd</au><au>Mahmood, Syed</au><au>Alheibshy, Fawaz</au><au>Alobaida, Ahmed</au><au>Abdul-Halim, Nadiya</au><au>Chatterjee, Bappaditya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A review on taste masked multiparticulate dosage forms for paediatric</atitle><jtitle>International journal of pharmaceutics</jtitle><addtitle>Int J Pharm</addtitle><date>2023-02-05</date><risdate>2023</risdate><volume>632</volume><spage>122571</spage><epage>122571</epage><pages>122571-122571</pages><artnum>122571</artnum><issn>0378-5173</issn><eissn>1873-3476</eissn><abstract>[Display omitted]
Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous contributing components such as swallowability, palatability (taste, flavour, texture, and mouthfeel), appearance, ease of administration, and patient characteristics. Multiparticulate as a dosage form is a platform technology for overcoming paediatrics' incapacity to swallow monolithic dosage forms, masking many medications' inherent nasty taste, and overcoming the obstacles of manufacturing a commercially taste masked dosage form. This review will discuss the considerations that must be taken into account to prepare taste masked multiparticulate dosage forms in the best way for paediatric use.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>36587776</pmid><doi>10.1016/j.ijpharm.2022.122571</doi><tpages>1</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-5173 |
| ispartof | International journal of pharmaceutics, 2023-02, Vol.632, p.122571-122571, Article 122571 |
| issn | 0378-5173 1873-3476 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Administration, Oral Chemistry, Pharmaceutical Child Dosage Forms Humans Multiparticulate system Paediatric Pediatrics Pharmaceutical Preparations Taste Taste masking Taste Perception Unpleasant drug |
| title | A review on taste masked multiparticulate dosage forms for paediatric |
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