Case of clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) due to Legionella pneumonia

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinicoradiologic syndrome diagnosed by temporary hyperintense lesion in the area, including the splenium of the corpus callosum, on diffusion-weighted imaging and neuropsychiatric symptoms that recover without...

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Veröffentlicht in:BMJ case reports 2022-12, Vol.15 (12), p.e252994
Hauptverfasser: Kageyama, Satoko, Hayashi, Ruiko, Uchida, Haruhito A
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Hayashi, Ruiko
Uchida, Haruhito A
description Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinicoradiologic syndrome diagnosed by temporary hyperintense lesion in the area, including the splenium of the corpus callosum, on diffusion-weighted imaging and neuropsychiatric symptoms that recover without sequelae. MERS is rare in adults, especially elderly people. We herein report a man in his 60s diagnosed with MERS caused by pneumonia. He completely recovered with only the administration of levofloxacin and azithromycin despite the risk factors of an advanced age, medical history of untreated hypertension, bilateral spontaneous pneumothoraxes, smoking and drinking habits and pulmonary emphysema. To our knowledge, this is the oldest case of MERS due to pneumonia and extremely old among total MERS cases. Our research revealed that species are the most common pathogens of adult-onset MERS, while viruses are the main causative factors in children. This case helps clarify the features of MERS in high-risk adults.
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MERS is rare in adults, especially elderly people. We herein report a man in his 60s diagnosed with MERS caused by pneumonia. He completely recovered with only the administration of levofloxacin and azithromycin despite the risk factors of an advanced age, medical history of untreated hypertension, bilateral spontaneous pneumothoraxes, smoking and drinking habits and pulmonary emphysema. To our knowledge, this is the oldest case of MERS due to pneumonia and extremely old among total MERS cases. Our research revealed that species are the most common pathogens of adult-onset MERS, while viruses are the main causative factors in children. 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subjects Adult
Adults
Age
Aged
Antigens
Blood
Brain Diseases - complications
Brain research
Cardiac arrhythmia
Case reports
Child
Children & youth
Coma
Consciousness
Corpus Callosum - diagnostic imaging
Corpus Callosum - pathology
Disease
Dysarthria
Encephalitis
Encephalitis - diagnostic imaging
Encephalitis - etiology
Etiology
Humans
Influenza
Laboratories
Legionella
Legionnaires' Disease - complications
Legionnaires' Disease - diagnosis
Legionnaires' Disease - drug therapy
Magnetic Resonance Imaging
Male
Patients
Pneumonia
Pneumonia - complications
Severe acute respiratory syndrome coronavirus 2
Viral infections
title Case of clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) due to Legionella pneumonia
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