Synthesis and antibacterial activity of novel 2‑fluoro ketolide antibiotics with 11,12‑quinoylalkyl side chains

A series of novel 2‑fluoro ketolide antibiotics with 11,12‑quinoylalkyl side chains derived from telithromycin and cethromycin were synthesized and evaluated for their antibacterial activities. [Display omitted] A series of novel 2‑fluoro ketolide antibiotics with 11,12‑quinoylalkyl side chains deri...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2023-01, Vol.80, p.129115-129115, Article 129115
Hauptverfasser:	Jin, Longlong, Zhang, Xiaoxi, Luo, Zhigang, Wu, Xianfu, Zhao, Zhehui
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Antibacterial activity Cethromycin Ketolides Macrolides Microbial Sensitivity Tests Quinolines Synthesis Telithromycin
Online-Zugang:	Volltext
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