Variability in Fetal Fraction Estimation: Comparing Fetal Fractions Reported by Noninvasive Prenatal Testing Providers Globally

Abstract Background Fetal fraction (FF) measurement is considered important for reliable noninvasive prenatal testing (NIPT). Using minimal FF threshold as a quality parameter is under debate. We evaluated the variability in reported FFs of individual samples between providers and laboratories and w...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2023-02, Vol.69 (2), p.160-167
Hauptverfasser:	Becking, Ellis C, Linthorst, Jasper, Patton, Simon, Gutowska-Ding, Weronika, Goodall, Rebecca, Khawaja, Farrah, Morgan, Fiona, Deans, Zandra, Chitty, Lyn S, Bekker, Mireille N, Scheffer, Peter G, Sistermans, Erik A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Female Fetus Genome Genomics Humans Noninvasive Prenatal Testing Pregnancy Prenatal Care Prenatal Diagnosis - methods
Online-Zugang:	Volltext
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