Nuciferine Ameliorates Nonesterified Fatty Acid-Induced Bovine Mammary Epithelial Cell Lipid Accumulation, Apoptosis, and Impaired Migration via Activating LKB1/AMPK Signaling Pathway

High blood concentrations of nonesterified fatty acids (NEFAs) provoke various metabolic disorders and are associated with mammary tissue injury and decreased milk production in dairy cows. Nuciferine, an alkaloid found in Nelumbo nucifera leaves, has great potential for correcting lipid metabolism...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2023-01, Vol.71 (1), p.443-456
Hauptverfasser:	Li, Jinxia, Zhao, Chenchen, Liu, Menglin, Chen, Linfang, Zhu, Yiwei, Gao, Wenwen, Du, Xiliang, Song, Yuxiang, Li, Xinwei, Liu, Guowen, Lei, Lin, Feng, Haihua
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-Activated Protein Kinase Kinases - metabolism AMP-Activated Protein Kinases - genetics AMP-Activated Protein Kinases - metabolism Animals Apoptosis Bioactive Constituents, Metabolites, and Functions Cattle Epithelial Cells - metabolism Fatty Acids, Nonesterified - toxicity Female Lipid Metabolism Signal Transduction
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