Lewis Acid-Promoted Three-Component Cyclization for the Construction of Functionalized Oxazoles

A simple and efficient synthetic strategy from amides, ynals, and sodium sulfinates via a Lewis acid-promoted three-component reaction has been reported. Thus, a broad range of various aryl (not alkyl)-substituted oxazoles could be synthesized via the formation of C–N, C–O, and C–S bonds in a one-po...

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Veröffentlicht in:Journal of organic chemistry 2023-01, Vol.88 (1), p.27-38
Hauptverfasser: Li, Anquan, Zhao, Jun, Zhang, Chen, Jiang, Qiuxia, Zhu, Baofu, Cao, Hua
Format: Artikel
Sprache:eng
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