Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway

Dysregulation of neuronal development may cause neurodevelopmental disorders. However, how to regulate embryonic neuronal development and whether this regulation can be medical interrupted are largely unknown. This study aimed to investigate whether and how andrographolide (ANP) regulates embryonic...

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Veröffentlicht in:	European journal of pharmacology 2023-02, Vol.940, p.175474-175474, Article 175474
Hauptverfasser:	Shi, Liangqin, Li, Hongfei, Wang, Zheng, Liu, Weiming, Wu, Xiao, Li, Jiali, Jin, Zhong, Hu, Wangming, Guo, Qiru, Zhang, Lingling, Wang, Yang, Liang, Bing, Zhu, Song, Zhang, Haidi, Xu, Huan, Yang, Lan, Shi, Riyi, Wang, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Andrographolide Animals Cell Proliferation Diterpenes - pharmacology Embryonic neuronal development Female Glycolysis Mice NeuN PFKFB3 Phosphofructokinase-2 - genetics Phosphofructokinase-2 - metabolism Phosphoric Monoester Hydrolases - metabolism Pregnancy TBR1
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