DABCO-promoted highly diastereo- and regioselective construction of C-3 functionalized spirooxindoles via 3 + 2 cycloaddition of 2-aryl/heteroarylidene-1H-indene-1,3(2H)-diones with N-2,2,2-trifluoroethylisatin ketimines at ambient conditions

The application of 2-aryl/heteroarylidene-1H-indene-1,3(2H)-dione as an activated olefin source in the DABCO-catalyzed [3 + 2] cycloaddition with N-2,2,2-trifluoroethylisatin ketimines has been disclosed. This highly efficient 1,3-dipolar cycloaddition reaction offered a variety of trifluoro methyl...

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Veröffentlicht in:RSC advances 2022-12, Vol.12 (54), p.34941
Hauptverfasser: Prasad, Madavi S, Bharani, Sankar, Sharief, Syed Mastan, Ravi, Mudavath, Sivaprakash, Murugesan, Borah, Biplob, Chowhan, L Raju
Format: Artikel
Sprache:eng
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