Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p

Salivary glands are physiologically orchestrated by the coordinated balance between cell differentiation, proliferation, apoptosis, and interactions between epithelial, mesenchymal endothelial, and neuronal cells, and they are frequent sites of manifestations of Sjögren's syndrome (SS) or IgG4-...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular cell research 2023-02, Vol.1870 (2), p.119404-119404, Article 119404
Hauptverfasser:	Hayashi, Yoshikazu, Kimura, Soi, Yano, Ena, Yoshimoto, Shohei, Saeki, Ayaka, Yasukochi, Atsushi, Hatakeyama, Yuji, Moriyama, Masafumi, Nakamura, Seiji, Jimi, Eijiro, Kawakubo-Yasukochi, Tomoyo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Differentiation Id4 IgG4-RD Immunoglobulin G4-Related Disease - diagnosis Immunoglobulin G4-Related Disease - genetics Immunoglobulin G4-Related Disease - metabolism Mice MicroRNAs - genetics MicroRNAs - metabolism miR-486-5p Salivary glands Salivary Glands - metabolism Sjogren's Syndrome - diagnosis Sjogren's Syndrome - genetics Sjogren's Syndrome - metabolism Submandibular Gland - metabolism Th17
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