Critical windows of early-life microbiota disruption on behaviour, neuroimmune function, and neurodevelopment

[Display omitted] •Critical windows exist: microbiota depletion in early life has enduring effects on the gut microbiota.•Early-life microbiota disruption induces subtle changes in circulating immune cells.•Evidence of sex and time-dependent effects on myelin-related gene expression.•Microglial morp...

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Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2023-02, Vol.108, p.309-327
Hauptverfasser: Lynch, Caoimhe M.K., Cowan, Caitlin S.M., Bastiaanssen, Thomaz F.S., Moloney, Gerard M., Theune, Nigel, van de Wouw, Marcel, Florensa Zanuy, Eva, Ventura-Silva, Ana Paula, Codagnone, Martin G., Villalobos-Manríquez, Francisca, Segalla, Matilde, Koc, Fatma, Stanton, Catherine, Ross, Paul, Dinan, Timothy G., Clarke, Gerard, Cryan, John F.
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Sprache:eng
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