Four‐Step Synthesis of (−)‐4‐epi‐Presilphiperfolan‐8α‐ol by Intramolecular Iron Hydride Atom Transfer‐Mediated Ketone‐Alkene Coupling and Studies to Access trans‐Hydrindanols with a Botryane Scaffold

From an (R)‐(+)‐pulegone‐derived building block that incorporates the stereo‐defined tertiary carbon bearing a methyl group, as found in the targeted sesquiterpenoid, a four‐step synthesis of (−)‐4‐epi‐presilphiperfolan‐8‐α‐ol was achieved. The key processes involved are a ring‐closing metathesis le...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemistry : a European journal 2023-03, Vol.29 (15), p.e202203286-n/a
Hauptverfasser:	Saladrigas, Mar, Gómez‐Bengoa, Enrique, Bonjoch, Josep, Bradshaw, Ben
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes Carbon Chemistry C−C coupling Hydrides Hydrogen atoms Ketones Metathesis natural products Pulegone radical reactions Radicals strained molecules Synthesis triquinanes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!