Evaluation of Positive Predictors of Micrometastasis in Central Lymph Nodes in Patients with Papillary Thyroid Cancer; A Cross-Sectional Study

Papillary thyroid cancer (PTC) is the most common primary cancer originating from thyroid follicular cells. The aim of this study was to evaluate the positive predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer. This was a cross-sectional study. The study p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Iranian Journal of Pathology 2022, Vol.17 (4), p.442-447
Hauptverfasser: Asherloo, Hamid, Nabipoorashrafi, Seyed Ali, Kashanizadeh, Atefeh, Moradi, Mohammad, Rezaei Tavirani, Majid, Baghai Wadji, Massoud
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 447
container_issue 4
container_start_page 442
container_title Iranian Journal of Pathology
container_volume 17
creator Asherloo, Hamid
Nabipoorashrafi, Seyed Ali
Kashanizadeh, Atefeh
Moradi, Mohammad
Rezaei Tavirani, Majid
Baghai Wadji, Massoud
description Papillary thyroid cancer (PTC) is the most common primary cancer originating from thyroid follicular cells. The aim of this study was to evaluate the positive predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer. This was a cross-sectional study. The study population was all known PTC patients who underwent total thyroidectomy and lymph node dissection of the central neck nodes based on the current indications. Confirmation of central lymph node involvement was performed by permanent smear after surgery. Data were analyzed using SPSS software version 22. A P-value below 0.05 was considered statistically significant. There was no significant relationship between age, gender, family history of PTC, family history of thyroid disease, multinodularity, history of other thyroid diseases, involvement of two thyroid lobes, and tumor grade with central lymph node involvement ( >0.05). There was a significant relationship between the tumor pathology and size with central lymph node involvement (
doi_str_mv 10.30699/IJP.2022.548679.2838
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2755803698</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2755803698</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2198-15ffe6b45115f1999907f2ba5557c95893f79d29aad5076efbe726aa19e760623</originalsourceid><addsrcrecordid>eNo9UdtOwzAMjRAIJtgngPLIS0eaLEkjnlDFVQMmDZ6jrHW1oLYpSQvaT_DNpAywItmxj4-dHIROUzJjRCh1cf-wnFFC6YzPMyHVjGYs20MTyuY8YYKLfTRJJeMJZ4QdoWkIb2Q0SYRkh-goQhgVTE7Q1_WHqQfTW9diV-GlC7a3H4CXHkpb9M6HMf1oC-8a6E2IxwZsW5xD23tT48W26Tb4yZXwk15GqlgJ-NP2m3jrbF0bv8Uvm613tsS5aQvwl_gK596FkKygGGdHolU_lNsTdFCZOsD01x-j15vrl_wuWTzf3udXi6SgqcqSlFcViPWcpzFKVTQiK7o2nHNZKJ4pVklVUmVMyYkUUK1BUmFMqkAKIig7Ruc73s679wFCrxsbCoi7tuCGoKnkPCNMqCxC-Q5ajAt7qHTnbRPfpFOif9TQ9q3Toxp6p4Ye1Yh9Z78jhnUD5X_X39-zb9Sxh0Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2755803698</pqid></control><display><type>article</type><title>Evaluation of Positive Predictors of Micrometastasis in Central Lymph Nodes in Patients with Papillary Thyroid Cancer; A Cross-Sectional Study</title><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Asherloo, Hamid ; Nabipoorashrafi, Seyed Ali ; Kashanizadeh, Atefeh ; Moradi, Mohammad ; Rezaei Tavirani, Majid ; Baghai Wadji, Massoud</creator><creatorcontrib>Asherloo, Hamid ; Nabipoorashrafi, Seyed Ali ; Kashanizadeh, Atefeh ; Moradi, Mohammad ; Rezaei Tavirani, Majid ; Baghai Wadji, Massoud</creatorcontrib><description>Papillary thyroid cancer (PTC) is the most common primary cancer originating from thyroid follicular cells. The aim of this study was to evaluate the positive predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer. This was a cross-sectional study. The study population was all known PTC patients who underwent total thyroidectomy and lymph node dissection of the central neck nodes based on the current indications. Confirmation of central lymph node involvement was performed by permanent smear after surgery. Data were analyzed using SPSS software version 22. A P-value below 0.05 was considered statistically significant. There was no significant relationship between age, gender, family history of PTC, family history of thyroid disease, multinodularity, history of other thyroid diseases, involvement of two thyroid lobes, and tumor grade with central lymph node involvement ( &gt;0.05). There was a significant relationship between the tumor pathology and size with central lymph node involvement ( &lt;0.05). Moreover, logistic multivariate regression analysis showed that female gender, multinodularity, and tumor size had a significant relationship with the incidence of central lymph node involvement ( &lt;0.05). Female gender, multinodularity, and larger tumor size may be predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer.</description><identifier>ISSN: 1735-5303</identifier><identifier>ISSN: 2345-3656</identifier><identifier>EISSN: 2345-3656</identifier><identifier>DOI: 10.30699/IJP.2022.548679.2838</identifier><identifier>PMID: 36532637</identifier><language>eng</language><publisher>Iran</publisher><ispartof>Iranian Journal of Pathology, 2022, Vol.17 (4), p.442-447</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36532637$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asherloo, Hamid</creatorcontrib><creatorcontrib>Nabipoorashrafi, Seyed Ali</creatorcontrib><creatorcontrib>Kashanizadeh, Atefeh</creatorcontrib><creatorcontrib>Moradi, Mohammad</creatorcontrib><creatorcontrib>Rezaei Tavirani, Majid</creatorcontrib><creatorcontrib>Baghai Wadji, Massoud</creatorcontrib><title>Evaluation of Positive Predictors of Micrometastasis in Central Lymph Nodes in Patients with Papillary Thyroid Cancer; A Cross-Sectional Study</title><title>Iranian Journal of Pathology</title><addtitle>Iran J Pathol</addtitle><description>Papillary thyroid cancer (PTC) is the most common primary cancer originating from thyroid follicular cells. The aim of this study was to evaluate the positive predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer. This was a cross-sectional study. The study population was all known PTC patients who underwent total thyroidectomy and lymph node dissection of the central neck nodes based on the current indications. Confirmation of central lymph node involvement was performed by permanent smear after surgery. Data were analyzed using SPSS software version 22. A P-value below 0.05 was considered statistically significant. There was no significant relationship between age, gender, family history of PTC, family history of thyroid disease, multinodularity, history of other thyroid diseases, involvement of two thyroid lobes, and tumor grade with central lymph node involvement ( &gt;0.05). There was a significant relationship between the tumor pathology and size with central lymph node involvement ( &lt;0.05). Moreover, logistic multivariate regression analysis showed that female gender, multinodularity, and tumor size had a significant relationship with the incidence of central lymph node involvement ( &lt;0.05). Female gender, multinodularity, and larger tumor size may be predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer.</description><issn>1735-5303</issn><issn>2345-3656</issn><issn>2345-3656</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNo9UdtOwzAMjRAIJtgngPLIS0eaLEkjnlDFVQMmDZ6jrHW1oLYpSQvaT_DNpAywItmxj4-dHIROUzJjRCh1cf-wnFFC6YzPMyHVjGYs20MTyuY8YYKLfTRJJeMJZ4QdoWkIb2Q0SYRkh-goQhgVTE7Q1_WHqQfTW9diV-GlC7a3H4CXHkpb9M6HMf1oC-8a6E2IxwZsW5xD23tT48W26Tb4yZXwk15GqlgJ-NP2m3jrbF0bv8Uvm613tsS5aQvwl_gK596FkKygGGdHolU_lNsTdFCZOsD01x-j15vrl_wuWTzf3udXi6SgqcqSlFcViPWcpzFKVTQiK7o2nHNZKJ4pVklVUmVMyYkUUK1BUmFMqkAKIig7Ruc73s679wFCrxsbCoi7tuCGoKnkPCNMqCxC-Q5ajAt7qHTnbRPfpFOif9TQ9q3Toxp6p4Ye1Yh9Z78jhnUD5X_X39-zb9Sxh0Q</recordid><startdate>2022</startdate><enddate>2022</enddate><creator>Asherloo, Hamid</creator><creator>Nabipoorashrafi, Seyed Ali</creator><creator>Kashanizadeh, Atefeh</creator><creator>Moradi, Mohammad</creator><creator>Rezaei Tavirani, Majid</creator><creator>Baghai Wadji, Massoud</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2022</creationdate><title>Evaluation of Positive Predictors of Micrometastasis in Central Lymph Nodes in Patients with Papillary Thyroid Cancer; A Cross-Sectional Study</title><author>Asherloo, Hamid ; Nabipoorashrafi, Seyed Ali ; Kashanizadeh, Atefeh ; Moradi, Mohammad ; Rezaei Tavirani, Majid ; Baghai Wadji, Massoud</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2198-15ffe6b45115f1999907f2ba5557c95893f79d29aad5076efbe726aa19e760623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asherloo, Hamid</creatorcontrib><creatorcontrib>Nabipoorashrafi, Seyed Ali</creatorcontrib><creatorcontrib>Kashanizadeh, Atefeh</creatorcontrib><creatorcontrib>Moradi, Mohammad</creatorcontrib><creatorcontrib>Rezaei Tavirani, Majid</creatorcontrib><creatorcontrib>Baghai Wadji, Massoud</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Iranian Journal of Pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asherloo, Hamid</au><au>Nabipoorashrafi, Seyed Ali</au><au>Kashanizadeh, Atefeh</au><au>Moradi, Mohammad</au><au>Rezaei Tavirani, Majid</au><au>Baghai Wadji, Massoud</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Positive Predictors of Micrometastasis in Central Lymph Nodes in Patients with Papillary Thyroid Cancer; A Cross-Sectional Study</atitle><jtitle>Iranian Journal of Pathology</jtitle><addtitle>Iran J Pathol</addtitle><date>2022</date><risdate>2022</risdate><volume>17</volume><issue>4</issue><spage>442</spage><epage>447</epage><pages>442-447</pages><issn>1735-5303</issn><issn>2345-3656</issn><eissn>2345-3656</eissn><abstract>Papillary thyroid cancer (PTC) is the most common primary cancer originating from thyroid follicular cells. The aim of this study was to evaluate the positive predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer. This was a cross-sectional study. The study population was all known PTC patients who underwent total thyroidectomy and lymph node dissection of the central neck nodes based on the current indications. Confirmation of central lymph node involvement was performed by permanent smear after surgery. Data were analyzed using SPSS software version 22. A P-value below 0.05 was considered statistically significant. There was no significant relationship between age, gender, family history of PTC, family history of thyroid disease, multinodularity, history of other thyroid diseases, involvement of two thyroid lobes, and tumor grade with central lymph node involvement ( &gt;0.05). There was a significant relationship between the tumor pathology and size with central lymph node involvement ( &lt;0.05). Moreover, logistic multivariate regression analysis showed that female gender, multinodularity, and tumor size had a significant relationship with the incidence of central lymph node involvement ( &lt;0.05). Female gender, multinodularity, and larger tumor size may be predictors of micrometastasis in central lymph nodes in patients with papillary thyroid cancer.</abstract><cop>Iran</cop><pmid>36532637</pmid><doi>10.30699/IJP.2022.548679.2838</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1735-5303
ispartof Iranian Journal of Pathology, 2022, Vol.17 (4), p.442-447
issn 1735-5303
2345-3656
2345-3656
language eng
recordid cdi_proquest_miscellaneous_2755803698
source DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central
title Evaluation of Positive Predictors of Micrometastasis in Central Lymph Nodes in Patients with Papillary Thyroid Cancer; A Cross-Sectional Study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T04%3A13%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluation%20of%20Positive%20Predictors%20of%20Micrometastasis%20in%20Central%20Lymph%20Nodes%20in%20Patients%20with%20Papillary%20Thyroid%20Cancer;%20A%20Cross-Sectional%20Study&rft.jtitle=Iranian%20Journal%20of%20Pathology&rft.au=Asherloo,%20Hamid&rft.date=2022&rft.volume=17&rft.issue=4&rft.spage=442&rft.epage=447&rft.pages=442-447&rft.issn=1735-5303&rft.eissn=2345-3656&rft_id=info:doi/10.30699/IJP.2022.548679.2838&rft_dat=%3Cproquest_cross%3E2755803698%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2755803698&rft_id=info:pmid/36532637&rfr_iscdi=true