Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause various syndromes that can lead to death. The aim of this study was to detect and genotype feline retroviruses in Mexican domestic cats. We used PCR assays t...
Gespeichert in:
| Veröffentlicht in: | Archives of virology 2023-01, Vol.168 (1), p.2-2, Article 2 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2 |
|---|---|
| container_issue | 1 |
| container_start_page | 2 |
| container_title | Archives of virology |
| container_volume | 168 |
| creator | Acevedo-Jiménez, Gabriel Eduardo Sarmiento-Silva, Rosa Elena Alonso-Morales, Rogelio Alejandro Córdova-Ponce, Rodolfo Ramírez-Álvarez, Hugo |
| description | Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause various syndromes that can lead to death. The aim of this study was to detect and genotype feline retroviruses in Mexican domestic cats. We used PCR assays to identify proviral DNA and viral RNA in 50 domestic cats with different clinical signs and hematological alterations. Endogenous FeLV (enFeLV) was identified in the genomic DNA of all cats in the study, and we detected transcripts of the LTR region of enFeLV in 48 individuals. Exogenous FeLV (exFeLV) was found in 13 cats. Furthermore, we detected FIV proviral DNA in 10 cats. The enFeLV sequences were shown to be the most variable, while the exFeLV sequences were highly conserved and related to previously reported subgroup A sequences. Sequencing of the FIV
gag
gene revealed the presence of subtype B in the infected cats. |
| doi_str_mv | 10.1007/s00705-022-05627-z |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2755800986</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2755800986</sourcerecordid><originalsourceid>FETCH-LOGICAL-c326t-91e25c1ed51f6ef73e929610ee15dbcdf682cf23013d13592b63efd8e9aa814a3</originalsourceid><addsrcrecordid>eNp9kc1uFDEQhC0EIpvAC3BAlrhwmeCftcdzjBIISJG4wNny2u1dRzN2YnsSZR8hT42ZDUTiwMWWur-qaqkQekfJKSWk_1TaQ0RHGOuIkKzv9i_Qiq4561Q_qJdoRThZd0oSdYSOS7kmpA24eI2OuBR8zYhYoccLqGBrSBGb6PAWItRgsd2ZbGyFHPZmWSaPPYwhAs5Qc7oLeS5QcIjYpQnKojG14PtQd9gF7yFDrNg2SbBmxCVsY1kidjCZmsa0XeZmbCFLRHmDXnkzFnj79J-gn18-_zj_2l19v_x2fnbVWc5k7QYKTFgKTlAvwfccBjZISgCocBvrvFTMesYJ5Y5yMbCN5OCdgsEYRdeGn6CPB9-bnG7ndrueQrEwjiZCmotmvRCKkEHJhn74B71Oc47tuoWSveiHvlHsQNmcSsng9U0Ok8kPmhL9uyl9aEq3pvTSlN430fsn63kzgfsr-VNNA_gBKG0Vt5Cfs_9j-wv8zKJe</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2755675797</pqid></control><display><type>article</type><title>Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Acevedo-Jiménez, Gabriel Eduardo ; Sarmiento-Silva, Rosa Elena ; Alonso-Morales, Rogelio Alejandro ; Córdova-Ponce, Rodolfo ; Ramírez-Álvarez, Hugo</creator><creatorcontrib>Acevedo-Jiménez, Gabriel Eduardo ; Sarmiento-Silva, Rosa Elena ; Alonso-Morales, Rogelio Alejandro ; Córdova-Ponce, Rodolfo ; Ramírez-Álvarez, Hugo</creatorcontrib><description>Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause various syndromes that can lead to death. The aim of this study was to detect and genotype feline retroviruses in Mexican domestic cats. We used PCR assays to identify proviral DNA and viral RNA in 50 domestic cats with different clinical signs and hematological alterations. Endogenous FeLV (enFeLV) was identified in the genomic DNA of all cats in the study, and we detected transcripts of the LTR region of enFeLV in 48 individuals. Exogenous FeLV (exFeLV) was found in 13 cats. Furthermore, we detected FIV proviral DNA in 10 cats. The enFeLV sequences were shown to be the most variable, while the exFeLV sequences were highly conserved and related to previously reported subgroup A sequences. Sequencing of the FIV
gag
gene revealed the presence of subtype B in the infected cats.</description><identifier>ISSN: 0304-8608</identifier><identifier>EISSN: 1432-8798</identifier><identifier>DOI: 10.1007/s00705-022-05627-z</identifier><identifier>PMID: 36534205</identifier><language>eng</language><publisher>Vienna: Springer Vienna</publisher><subject>Animals ; Biology ; Biomedical and Life Sciences ; Biomedicine ; Brief Report ; Cats ; Deoxyribonucleic acid ; Disease ; DNA ; Domestic animals ; Feline leukemia ; Gag protein ; Genes ; Genomes ; Genotypes ; Hematology ; Immune system ; Immunodeficiency Virus, Feline - genetics ; Infections ; Infectious Diseases ; Leukemia ; Leukemia Virus, Feline - genetics ; Leukemia, Feline ; Lymphoma ; Medical Microbiology ; Nucleotide sequence ; Proviruses - genetics ; Retroviridae ; Veterinary medicine ; Virology ; Viruses</subject><ispartof>Archives of virology, 2023-01, Vol.168 (1), p.2-2, Article 2</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c326t-91e25c1ed51f6ef73e929610ee15dbcdf682cf23013d13592b63efd8e9aa814a3</cites><orcidid>0000-0003-1682-8104 ; 0000-0001-7430-5657 ; 0000-0002-2026-9918 ; 0000-0002-4159-1682</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00705-022-05627-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00705-022-05627-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36534205$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Acevedo-Jiménez, Gabriel Eduardo</creatorcontrib><creatorcontrib>Sarmiento-Silva, Rosa Elena</creatorcontrib><creatorcontrib>Alonso-Morales, Rogelio Alejandro</creatorcontrib><creatorcontrib>Córdova-Ponce, Rodolfo</creatorcontrib><creatorcontrib>Ramírez-Álvarez, Hugo</creatorcontrib><title>Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations</title><title>Archives of virology</title><addtitle>Arch Virol</addtitle><addtitle>Arch Virol</addtitle><description>Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause various syndromes that can lead to death. The aim of this study was to detect and genotype feline retroviruses in Mexican domestic cats. We used PCR assays to identify proviral DNA and viral RNA in 50 domestic cats with different clinical signs and hematological alterations. Endogenous FeLV (enFeLV) was identified in the genomic DNA of all cats in the study, and we detected transcripts of the LTR region of enFeLV in 48 individuals. Exogenous FeLV (exFeLV) was found in 13 cats. Furthermore, we detected FIV proviral DNA in 10 cats. The enFeLV sequences were shown to be the most variable, while the exFeLV sequences were highly conserved and related to previously reported subgroup A sequences. Sequencing of the FIV
gag
gene revealed the presence of subtype B in the infected cats.</description><subject>Animals</subject><subject>Biology</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Brief Report</subject><subject>Cats</subject><subject>Deoxyribonucleic acid</subject><subject>Disease</subject><subject>DNA</subject><subject>Domestic animals</subject><subject>Feline leukemia</subject><subject>Gag protein</subject><subject>Genes</subject><subject>Genomes</subject><subject>Genotypes</subject><subject>Hematology</subject><subject>Immune system</subject><subject>Immunodeficiency Virus, Feline - genetics</subject><subject>Infections</subject><subject>Infectious Diseases</subject><subject>Leukemia</subject><subject>Leukemia Virus, Feline - genetics</subject><subject>Leukemia, Feline</subject><subject>Lymphoma</subject><subject>Medical Microbiology</subject><subject>Nucleotide sequence</subject><subject>Proviruses - genetics</subject><subject>Retroviridae</subject><subject>Veterinary medicine</subject><subject>Virology</subject><subject>Viruses</subject><issn>0304-8608</issn><issn>1432-8798</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kc1uFDEQhC0EIpvAC3BAlrhwmeCftcdzjBIISJG4wNny2u1dRzN2YnsSZR8hT42ZDUTiwMWWur-qaqkQekfJKSWk_1TaQ0RHGOuIkKzv9i_Qiq4561Q_qJdoRThZd0oSdYSOS7kmpA24eI2OuBR8zYhYoccLqGBrSBGb6PAWItRgsd2ZbGyFHPZmWSaPPYwhAs5Qc7oLeS5QcIjYpQnKojG14PtQd9gF7yFDrNg2SbBmxCVsY1kidjCZmsa0XeZmbCFLRHmDXnkzFnj79J-gn18-_zj_2l19v_x2fnbVWc5k7QYKTFgKTlAvwfccBjZISgCocBvrvFTMesYJ5Y5yMbCN5OCdgsEYRdeGn6CPB9-bnG7ndrueQrEwjiZCmotmvRCKkEHJhn74B71Oc47tuoWSveiHvlHsQNmcSsng9U0Ok8kPmhL9uyl9aEq3pvTSlN430fsn63kzgfsr-VNNA_gBKG0Vt5Cfs_9j-wv8zKJe</recordid><startdate>20230101</startdate><enddate>20230101</enddate><creator>Acevedo-Jiménez, Gabriel Eduardo</creator><creator>Sarmiento-Silva, Rosa Elena</creator><creator>Alonso-Morales, Rogelio Alejandro</creator><creator>Córdova-Ponce, Rodolfo</creator><creator>Ramírez-Álvarez, Hugo</creator><general>Springer Vienna</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P64</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1682-8104</orcidid><orcidid>https://orcid.org/0000-0001-7430-5657</orcidid><orcidid>https://orcid.org/0000-0002-2026-9918</orcidid><orcidid>https://orcid.org/0000-0002-4159-1682</orcidid></search><sort><creationdate>20230101</creationdate><title>Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations</title><author>Acevedo-Jiménez, Gabriel Eduardo ; Sarmiento-Silva, Rosa Elena ; Alonso-Morales, Rogelio Alejandro ; Córdova-Ponce, Rodolfo ; Ramírez-Álvarez, Hugo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-91e25c1ed51f6ef73e929610ee15dbcdf682cf23013d13592b63efd8e9aa814a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Animals</topic><topic>Biology</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Brief Report</topic><topic>Cats</topic><topic>Deoxyribonucleic acid</topic><topic>Disease</topic><topic>DNA</topic><topic>Domestic animals</topic><topic>Feline leukemia</topic><topic>Gag protein</topic><topic>Genes</topic><topic>Genomes</topic><topic>Genotypes</topic><topic>Hematology</topic><topic>Immune system</topic><topic>Immunodeficiency Virus, Feline - genetics</topic><topic>Infections</topic><topic>Infectious Diseases</topic><topic>Leukemia</topic><topic>Leukemia Virus, Feline - genetics</topic><topic>Leukemia, Feline</topic><topic>Lymphoma</topic><topic>Medical Microbiology</topic><topic>Nucleotide sequence</topic><topic>Proviruses - genetics</topic><topic>Retroviridae</topic><topic>Veterinary medicine</topic><topic>Virology</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Acevedo-Jiménez, Gabriel Eduardo</creatorcontrib><creatorcontrib>Sarmiento-Silva, Rosa Elena</creatorcontrib><creatorcontrib>Alonso-Morales, Rogelio Alejandro</creatorcontrib><creatorcontrib>Córdova-Ponce, Rodolfo</creatorcontrib><creatorcontrib>Ramírez-Álvarez, Hugo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Acevedo-Jiménez, Gabriel Eduardo</au><au>Sarmiento-Silva, Rosa Elena</au><au>Alonso-Morales, Rogelio Alejandro</au><au>Córdova-Ponce, Rodolfo</au><au>Ramírez-Álvarez, Hugo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations</atitle><jtitle>Archives of virology</jtitle><stitle>Arch Virol</stitle><addtitle>Arch Virol</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>168</volume><issue>1</issue><spage>2</spage><epage>2</epage><pages>2-2</pages><artnum>2</artnum><issn>0304-8608</issn><eissn>1432-8798</eissn><abstract>Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause various syndromes that can lead to death. The aim of this study was to detect and genotype feline retroviruses in Mexican domestic cats. We used PCR assays to identify proviral DNA and viral RNA in 50 domestic cats with different clinical signs and hematological alterations. Endogenous FeLV (enFeLV) was identified in the genomic DNA of all cats in the study, and we detected transcripts of the LTR region of enFeLV in 48 individuals. Exogenous FeLV (exFeLV) was found in 13 cats. Furthermore, we detected FIV proviral DNA in 10 cats. The enFeLV sequences were shown to be the most variable, while the exFeLV sequences were highly conserved and related to previously reported subgroup A sequences. Sequencing of the FIV
gag
gene revealed the presence of subtype B in the infected cats.</abstract><cop>Vienna</cop><pub>Springer Vienna</pub><pmid>36534205</pmid><doi>10.1007/s00705-022-05627-z</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0003-1682-8104</orcidid><orcidid>https://orcid.org/0000-0001-7430-5657</orcidid><orcidid>https://orcid.org/0000-0002-2026-9918</orcidid><orcidid>https://orcid.org/0000-0002-4159-1682</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-8608 |
| ispartof | Archives of virology, 2023-01, Vol.168 (1), p.2-2, Article 2 |
| issn | 0304-8608 1432-8798 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2755800986 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Animals Biology Biomedical and Life Sciences Biomedicine Brief Report Cats Deoxyribonucleic acid Disease DNA Domestic animals Feline leukemia Gag protein Genes Genomes Genotypes Hematology Immune system Immunodeficiency Virus, Feline - genetics Infections Infectious Diseases Leukemia Leukemia Virus, Feline - genetics Leukemia, Feline Lymphoma Medical Microbiology Nucleotide sequence Proviruses - genetics Retroviridae Veterinary medicine Virology Viruses |
| title | Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T00%3A36%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Detection%20and%20genetic%20characterization%20of%20feline%20retroviruses%20in%20domestic%20cats%20with%20different%20clinical%20signs%20and%20hematological%20alterations&rft.jtitle=Archives%20of%20virology&rft.au=Acevedo-Jim%C3%A9nez,%20Gabriel%20Eduardo&rft.date=2023-01-01&rft.volume=168&rft.issue=1&rft.spage=2&rft.epage=2&rft.pages=2-2&rft.artnum=2&rft.issn=0304-8608&rft.eissn=1432-8798&rft_id=info:doi/10.1007/s00705-022-05627-z&rft_dat=%3Cproquest_cross%3E2755800986%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2755675797&rft_id=info:pmid/36534205&rfr_iscdi=true |