Part I: Significant reduction of lyophilization process times by using novel matrix based scaffolds

[Display omitted] To improve the long-term stability of drugs with limited stability (e.g., biologicals such as monoclonal antibodies, antibody drug conjugates or peptides), some pharmaceuticals endure a lengthy and cost-intensive process called lyophilization. While the shelf life of lyophilized dr...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2023-03, Vol.184, p.248-261
Hauptverfasser:	Kullmann, Daniel, Martinez, Carmen Lema, Lümkemann, Jörg, Huwyler, Jörg
Format:	Artikel
Sprache:	eng
Schlagworte:	3D-printing Intermediate process container Lyophilization Monoclonal antibody Porous structure
Online-Zugang:	Volltext
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