PLZF promotes the development of asthma tolerance via affecting memory phenotypes of immune cells

•Promyelocytic leukemia zinc finger (PLZF) is upregulated in asthma tolerant lungs.•Memory cells are higher in asthmatic mice than asthma tolerant mice.•Overexpression or knock down of Zbtb16 (encoding PLZF) affects expressions of CD44 and levels of memory cells.•PLZF+ cells are downregulated after...

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Veröffentlicht in:	International immunopharmacology 2023-01, Vol.114, p.109559-109559, Article 109559
Hauptverfasser:	Li, Na, Shi, Tianyun, Zhang, Meng, He, Yanchao, Feng, Jingjing, Mei, Zhoufang, Su, Xiao, Jie, Zhijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma Asthma - immunology Asthma - metabolism Asthma tolerance Hyaluronan Receptors Lung Lymphocytes Memory phenotypes Mice Ovalbumin Phenotype Promyelocytic Leukemia Zinc Finger Protein - metabolism PZLF Respiratory syncytial virus Respiratory Syncytial Virus Infections - immunology Respiratory Syncytial Virus Infections - metabolism
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